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» Authors » Fleur S van de Bovenkamp

Fleur S van de Bovenkamp

Explore the profile of Fleur S van de Bovenkamp including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 443
Followers 0
Related Specialties
Allergy & Immunology
Science
Rheumatology
Top 10 Co-Authors
Theo Rispens
Ninotska I L Derksen
Gestur Vidarsson
Manfred Wuhrer
Pleuni Ooijevaar-De Heer
Leendert A Trouw
Douwe J Dijkstra
Lise Hafkenscheid
Kyra A Gelderman
Paul W H I Parren
Published In
Sci Rep
Ann Rheum Dis
J Immunol
Proc Natl Acad Sci U S A
Front Immunol
Affiliations
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Recent Articles
11.
Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies
van Schie K, Kruithof S, Ooijevaar-De Heer P, Derksen N, van de Bovenkamp F, Saris A, et al.
Ann Rheum Dis . 2018 Jun; 77(10):1471-1479. PMID: 29945923
Objectives: Therapeutic antibodies can provoke an antidrug antibody (ADA) response, which can form soluble immune complexes with the drug in potentially high amounts. Nevertheless, ADA-associated adverse events are usually rare,...
12.
Variable Domain -Linked Glycans Acquired During Antigen-Specific Immune Responses Can Contribute to Immunoglobulin G Antibody Stability
van de Bovenkamp F, Derksen N, van Breemen M, de Taeye S, Ooijevaar-De Heer P, Sanders R, et al.
Front Immunol . 2018 May; 9:740. PMID: 29706962
Immunoglobulin G (IgG) can contain -linked glycans in the variable domains, the so-called Fab glycans, in addition to the Fc glycans in the C2 domains. These Fab glycans are acquired...
13.
Adaptive antibody diversification through -linked glycosylation of the immunoglobulin variable region
van de Bovenkamp F, Derksen N, Ooijevaar-De Heer P, van Schie K, Kruithof S, Berkowska M, et al.
Proc Natl Acad Sci U S A . 2018 Feb; 115(8):1901-1906. PMID: 29432186
A hallmark of B-cell immunity is the generation of a diverse repertoire of antibodies from a limited set of germline V(D)J genes. This repertoire is usually defined in terms of...
14.
The extensive glycosylation of the ACPA variable domain observed for ACPA-IgG is absent from ACPA-IgM
Kempers A, Hafkenscheid L, Dorjee A, Moutousidou E, van de Bovenkamp F, Rispens T, et al.
Ann Rheum Dis . 2017 Jul; 77(7):1087-1088. PMID: 28747327
No abstract available.
15.
Decreased IL7Rα and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin
Rother M, Jensen K, van der Burg M, van de Bovenkamp F, Kroek R, van IJcken W, et al.
Sci Rep . 2016 Sep; 6:33924. PMID: 27658954
Newborns are unable to mount antibody responses towards certain antigens. This has been related to the restricted repertoire of immunoglobulin (Ig) genes of their B cells. The mechanisms underlying the...
16.
The Emerging Importance of IgG Fab Glycosylation in Immunity
van de Bovenkamp F, Hafkenscheid L, Rispens T, Rombouts Y
J Immunol . 2016 Feb; 196(4):1435-41. PMID: 26851295
Human IgG is the most abundant glycoprotein in serum and is crucial for protective immunity. In addition to conserved IgG Fc glycans, ∼15-25% of serum IgG contains glycans within the...
17.
Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages
Nagelkerke S, Dekkers G, Kustiawan I, van de Bovenkamp F, Geissler J, Plomp R, et al.
Blood . 2014 Oct; 124(25):3709-18. PMID: 25352126
In immune thrombocytopenia and warm autoimmune hemolytic anemia, circulating immunoglobulin G (IgG)-opsonized blood cells are cleared from the circulation by macrophages. Administration of intravenous immunoglobulin (IVIg) can prevent uptake, but...