Flavia Sacerdoti
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Explore the profile of Flavia Sacerdoti including associated specialties, affiliations and a list of published articles.
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23
Citations
131
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Recent Articles
1.
Gomez F, Reppetti J, Alvarez R, Giron Reyes D, Sacerdoti F, Balestracci A, et al.
Biochim Biophys Acta Mol Cell Res
. 2024 Oct;
1872(1):119866.
PMID: 39442808
One of the hallmarks of Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome (STEC-HUS) is kidney damage. Our previous research demonstrated that Shiga toxin type 2 (Stx2a) decreases cell viability and...
2.
Fischer Sigel L, Sanchez D, Sacerdoti F, Zotta E, Silberstein C
Microb Pathog
. 2023 Dec;
186:106482.
PMID: 38086442
Background: Shiga toxin-producing Escherichia coli is the main cause of post-diarrheal hemolytic uremic syndrome (HUS) which produces acute kidney injury mainly in children, although it can also affect adults. The...
3.
Sacerdoti F, Gomez F, Jancic C, Lombardo T, Pascuale C, Moretton M, et al.
Toxicon
. 2023 Nov;
236:107349.
PMID: 37979924
Shiga toxin producing Escherichia coli (STEC) are foodborne pathogens that release Shiga toxin (Stx), virulence factor responsible for the development of Hemolytic Uremic Syndrome (HUS). Stx causes endothelial cell damage,...
4.
Fernandez-Brando R, Sacerdoti F, Amaral M, Bernal A, Da Rocha M, Belardo M, et al.
Rev Argent Microbiol
. 2023 Sep;
56(1):25-32.
PMID: 37704516
In Argentina, hemolytic uremic syndrome (HUS) caused by EHEC has the highest incidence in the world. EHEC infection has an endemo-epidemic behavior, causing 20-30% of acute bloody diarrhea syndrome in...
5.
Martire-Greco D, La Greca A, Montanez L, Biani C, Lombardi A, Birnberg-Weiss F, et al.
Shock
. 2023 Apr;
59(6):941-947.
PMID: 37036956
Background : Mesenchymal stem cells (MSCs) can be activated by different bacterial toxins. Lipopolysaccharides and Shiga Toxin (Stx) are the main toxins necessary for hemolytic uremic syndrome development. The main...
6.
Scalise M, Garimano N, Sanz M, Padola N, Leonino P, Pereyra A, et al.
Front Endocrinol (Lausanne)
. 2022 Aug;
13:945736.
PMID: 35957815
The presence of in the vaginal microbiome has been associated with pregnancy complications. In previous works, we demonstrated that Shiga toxin-producing (STEC) can produce abortion and premature delivery in rats...
7.
Henrique I, Sacerdoti F, Ferreira R, Henrique C, Amaral M, Piazza R, et al.
Front Cell Infect Microbiol
. 2022 Feb;
12:825856.
PMID: 35223548
Shiga toxins (Stx) are AB-type toxins, composed of five B subunits which bind to Gb host cell receptors and an active A subunit, whose action on the ribosome leads to...
8.
Luz D, Gomez F, Ferreira R, Melo B, Guth B, Quintilio W, et al.
Toxins (Basel)
. 2021 Nov;
13(11).
PMID: 34822608
Hemolytic Uremic Syndrome (HUS) associated with Shiga-toxigenic (STEC) infections is the principal cause of acute renal injury in pediatric age groups. Shiga toxin type 2 (Stx2) has in vitro cytotoxic...
9.
Alvarez R, Gomez F, Zotta E, Paton A, Paton J, Ibarra C, et al.
Toxins (Basel)
. 2021 Aug;
13(8).
PMID: 34437406
Shiga toxin-producing (STEC) produces Stx1 and/or Stx2, and Subtilase cytotoxin (SubAB). Since these toxins may be present simultaneously during STEC infections, the purpose of this work was to study the...
10.
Ribeiro I, Souto P, Borbely A, Lira Tanabe E, Cadavid A, Alvarez A, et al.
Syst Biol Reprod Med
. 2020 Jun;
66(3):151-169.
PMID: 32482148
Abbreviations: ADE: antibody-dependent enhancement; CCL2: monocyte chemoattractant protein-1; CCL3: macrophage inflammatory protein-1 α; CCL5: chemokine (C-C motif) ligand 5; CHIKV: chikungunya virus; DCL: diffuse cutaneous leishmaniasis; DENV: dengue virus; Gb3:...