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Flavia Niccolini

Explore the profile of Flavia Niccolini including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 965
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Recent Articles
1.
Wilson H, Pagano G, Yousaf T, Polychronis S, De Micco R, Giordano B, et al.
J Neural Transm (Vienna) . 2022 Mar; 129(10):1311. PMID: 35230538
No abstract available.
2.
Wilson H, Pagano G, Yousaf T, Polychronis S, De Micco R, Giordano B, et al.
J Neural Transm (Vienna) . 2019 Dec; 127(1):51-59. PMID: 31853652
Over the course of the disease, about 80% of Parkinson's disease patients will develop cognitive impairment. However, predictive factors associated with cognitive decline are still under investigation. Here, we investigated...
3.
Niccolini F, Wilson H, Giordano B, Diamantopoulos K, Pagano G, Chaudhuri K, et al.
BMC Neurosci . 2019 Oct; 20(1):55. PMID: 31640554
Background: Non-motor symptoms are common aspects of Parkinson's disease (PD) occurring even at the prodromal stage of the disease and greatly affecting the quality of life. Here, we investigated whether...
4.
Polychronis S, Dervenoulas G, Yousaf T, Niccolini F, Pagano G, Politis M
PLoS One . 2019 Jul; 14(7):e0214352. PMID: 31344030
Background: The underlying pathophysiology of dysphagia is multifactorial and evidence clarifying the precise mechanisms are scarce. Dysfunction in dopamine-related and non-dopamine-related pathways, changes in cortical networks related with swallowing and...
5.
Pagano G, Niccolini F, Wilson H, Yousaf T, Khan N, Martino D, et al.
Mov Disord . 2019 Jun; 34(10):1505-1515. PMID: 31158314
Background: Recent work has shown loss of phosphodiesterase 10A levels in middle-stage and advanced treated patients with PD, which was associated with motor symptom severity. Objectives: To assess phosphodiesterase 10A...
6.
Polychronis S, Niccolini F, Pagano G, Yousaf T, Politis M
Parkinsonism Relat Disord . 2019 May; 64:256-261. PMID: 31078401
Introduction: Speech difficulties are a common debilitating feature of Parkinson's disease and we aimed to investigate whether speech difficulties are associated with striatal dopaminergic deficits and faster disease progression. Methods:...
7.
Giannetti P, Niccolini F, Nicholas R
Degener Neurol Neuromuscul Dis . 2019 Mar; 2:119-132. PMID: 30890883
Multiple sclerosis (MS) arises from an immune attack on the central nervous system producing demyelination and axonal loss. Clinically the relapsing-remitting course is characterized by subacute onset of neurological symptoms...
8.
Wilson H, Pagano G, Niccolini F, Muhlert N, Mehta M, Searle G, et al.
Parkinsonism Relat Disord . 2019 Mar; 77:163-169. PMID: 30824285
Introduction: Preclinical studies suggest a link between cAMP/PKA signalling, phosphodiesterase 4 (PDE4) expression and excessive daytime sleepiness (EDS). Here, we investigated in vivo the association between PDE4 expression and EDS...
9.
Yousaf T, Pagano G, Niccolini F, Politis M
J Neurol . 2019 Mar; 266(5):1203-1210. PMID: 30820739
Objectives: To investigate whether baseline [I]FP-CIT SPECT and CSF markers can predict cognitive impairment (CI) in PD patients, and provide a profile of those most at risk. Methods: 262 de...
10.
Wilson H, Niccolini F, Pellicano C, Politis M
J Neurol Sci . 2019 Jan; 398:31-38. PMID: 30682518
Background: Imaging studies have revealed cortical thinning and subcortical atrophy occurring in Parkinson's disease (PD); however, the topographical distribution and clinical associations related to advancing stages of PD remains unclear....