Flavia Castellano
Overview
Explore the profile of Flavia Castellano including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
573
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Recent Articles
1.
Ferrara B, Bourgoin-Voillard S, Habert D, Vallee B, Nicolas-Boluda A, Simanic I, et al.
Proteomics
. 2024 Sep;
24(23-24):e2400058.
PMID: 39279557
The fibrotic stroma characterizing pancreatic ductal adenocarcinoma (PDAC) derives from a progressive tissue rigidification, which induces epithelial mesenchymal transition and metastatic dissemination. The aim of this study was to investigate...
2.
Bekkat F, Seradj M, Lengagne R, Fiore F, Kato M, Lucas B, et al.
Eur J Immunol
. 2024 Feb;
54(4):e2350615.
PMID: 38400692
B cells present in human cutaneous melanoma have been associated with protective or detrimental effects on disease progression according to their phenotype. By using the RET model of spontaneous melanoma...
3.
Faure-Dupuy S, Jubrail J, Depierre M, Africano-Gomez K, Oberg L, Israelsson E, et al.
EMBO Rep
. 2024 Feb;
25(3):1156-1175.
PMID: 38332148
Human rhinovirus is the most frequently isolated virus during severe exacerbations of chronic respiratory diseases, like chronic obstructive pulmonary disease. In this disease, alveolar macrophages display significantly diminished phagocytic functions...
4.
Gatineau J, Nidercorne C, Dupont A, Puiffe M, Cohen J, Molinier-Frenkel V, et al.
Front Immunol
. 2022 Sep;
13:982839.
PMID: 36131918
The secreted enzyme interleukin four-induced gene 1 (IL4I1) is involved in the negative control of the adaptive immune response. IL4I1 expression in human cancer is frequent and correlates with poor...
5.
Castellano F, Prevost-Blondel A, Cohen J, Molinier-Frenkel V
Oncoimmunology
. 2021 May;
10(1):1924500.
PMID: 34026337
The amino-acid catabolizing enzyme Interleukin-4 induced gene 1 (IL4I1) remains poorly characterized despite it is emerging as a pertinent therapeutic target for cancer. IL4I1 is secreted in the synaptic cleft...
6.
Castellano F, Correale J, Molinier-Frenkel V
Front Immunol
. 2021 May;
12:689864.
PMID: 34025686
No abstract available.
7.
Castellano F, Molinier-Frenkel V
Front Cell Dev Biol
. 2021 Jan;
8:613416.
PMID: 33392202
Amino acids are essential for protein synthesis, epigenetic modification through the methylation of histones, and the maintenance of a controlled balance of oxidoreduction via the production of glutathione and are...
8.
Puiffe M, Dupont A, Sako N, Gatineau J, Cohen J, Mestivier D, et al.
Front Immunol
. 2020 Dec;
11:600012.
PMID: 33343572
IL4I1 is an immunoregulatory enzyme that inhibits CD8 T-cell proliferation and in the tumoral context. Here, we dissected the effect of IL4I1 on CD8 T-cell priming by studying the differentiation...
9.
Presset M, Djordjevic D, Dupont A, Le Gall E, Molinier-Frenkel V, Castellano F
Bioorg Chem
. 2019 Dec;
94:103463.
PMID: 31812258
No abstract available.
10.
Molinier-Frenkel V, Prevost-Blondel A, Castellano F
Cells
. 2019 Jul;
8(7).
PMID: 31330829
The high metabolic needs of T lymphocytes in response to activation make them particularly vulnerable to modifications of their biochemical milieu. Immunosuppressive enzymes produced in the tumor microenvironment modify nutrient...