Fitz Gerald S Silao
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Explore the profile of Fitz Gerald S Silao including associated specialties, affiliations and a list of published articles.
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10
Citations
241
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Recent Articles
1.
Silao F, Valeriano V, Uddstrom E, Falconer E, Ljungdahl P
Mol Microbiol
. 2024 Jan;
121(4):696-716.
PMID: 38178569
Candida albicans has the capacity to neutralize acidic growth environments by releasing ammonia derived from the catabolism of amino acids. The molecular components underlying alkalization and its physiological significance remain...
2.
Silao F, Jiang T, Bereczky-Veress B, Kuhbacher A, Ryman K, Uwamohoro N, et al.
PLoS Pathog
. 2023 Nov;
19(11):e1011677.
PMID: 37917600
Candida albicans, the primary etiology of human mycoses, is well-adapted to catabolize proline to obtain energy to initiate morphological switching (yeast to hyphal) and for growth. We report that put1-/-...
3.
Silao F, Ljungdahl P
Pathogens
. 2022 Jan;
11(1).
PMID: 35055954
Nutrient uptake is essential for cellular life and the capacity to perceive extracellular nutrients is critical for coordinating their uptake and metabolism. Commensal fungal pathogens, e.g., , have evolved in...
4.
Silao F, Ryman K, Jiang T, Ward M, Hansmann N, Molenaar C, et al.
PLoS Pathog
. 2021 Aug;
17(8):e1009877.
PMID: 34460867
[This corrects the article DOI: 10.1371/journal.ppat.1008328.].
5.
Silao F, Ryman K, Jiang T, Ward M, Hansmann N, Molenaar C, et al.
PLoS Pathog
. 2020 Sep;
16(9):e1008328.
PMID: 32936835
Candida albicans cells depend on the energy derived from amino acid catabolism to induce and sustain hyphal growth inside phagosomes of engulfing macrophages. The concomitant deamination of amino acids is...
6.
Silao F, Ward M, Ryman K, Wallstrom A, Brindefalk B, Udekwu K, et al.
PLoS Genet
. 2019 Feb;
15(2):e1007976.
PMID: 30742618
Amino acids are among the earliest identified inducers of yeast-to-hyphal transitions in Candida albicans, an opportunistic fungal pathogen of humans. Here, we show that the morphogenic amino acids arginine, ornithine...
7.
Chen Y, Yu S, Huang H, Chang Y, Lehman V, Silao F, et al.
Eukaryot Cell
. 2014 Jan;
13(7):844-54.
PMID: 24442892
Candida tropicalis, a species closely related to Candida albicans, is an emerging fungal pathogen associated with high mortality rates of 40 to 70%. Like C. albicans and Candida dubliniensis, C....
8.
Zhang J, Silao F, Bigol U, Bungay A, G Nicolas M, Heitman J, et al.
PLoS One
. 2012 Sep;
7(8):e44192.
PMID: 22952924
Candida lusitaniae is an emerging fungal pathogen that infects immunocompromised patients including HIV/AIDS, cancer, and neonatal pediatric patients. Though less prevalent than other Candida species, C. lusitaniae is unique in...
9.
Chen Y, Konieczka J, Springer D, Bowen S, Zhang J, Silao F, et al.
G3 (Bethesda)
. 2012 Jun;
2(6):675-91.
PMID: 22690377
Candida glabrata is an emerging human fungal pathogen that is frequently drug tolerant, resulting in difficulties in treatment and a higher mortality in immunocompromised patients. The calcium-activated protein phosphatase calcineurin...
10.
Chen Y, Brand A, Morrison E, Silao F, Bigol U, Malbas Jr F, et al.
Eukaryot Cell
. 2011 May;
10(6):803-19.
PMID: 21531874
Candida dubliniensis is an emerging pathogenic yeast species closely related to Candida albicans and frequently found colonizing or infecting the oral cavities of HIV/AIDS patients. Drug resistance during C. dubliniensis...