Filomena A Carvalho
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Explore the profile of Filomena A Carvalho including associated specialties, affiliations and a list of published articles.
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47
Citations
669
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Recent Articles
1.
Martins A, Carvalho F, Nascimento A, Silva N, Rebelo T, Faustino A, et al.
Protein Sci
. 2024 Aug;
33(9):e5142.
PMID: 39194132
Zika virus (ZIKV), a mosquito-borne Flavivirus of international concern, causes congenital microcephaly in newborns and Guillain-Barré syndrome in adults. ZIKV capsid (C) protein, one of three key structural proteins, is...
2.
Domingues N, Catarino S, Cristovao B, Rodrigues L, Carvalho F, Sarmento M, et al.
EMBO J
. 2024 Jul;
43(17):3627-3649.
PMID: 39044100
A robust and efficient cellular response to lysosomal membrane damage prevents leakage from the lysosome lumen into the cytoplasm. This response is understood to happen through either lysosomal membrane repair...
3.
Lopes C, Pronto-Laborinho A, Conceicao V, Freitas T, Matias G, Gromicho M, et al.
Biofactors
. 2023 Dec;
50(3):558-571.
PMID: 38149762
Erythrocytes play a fundamental role in oxygen delivery to tissues and binding to inflammatory mediators. Evidences suggest that dysregulated erythrocyte function could contribute to the pathophysiology of several neurodegenerative diseases....
4.
Lopes C, Curty J, Carvalho F, Hernandez-Machado A, Kinoshita K, Santos N, et al.
Commun Biol
. 2023 Feb;
6(1):192.
PMID: 36801914
Erythrocytes are deformable cells that undergo progressive biophysical and biochemical changes affecting the normal blood flow. Fibrinogen, one of the most abundant plasma proteins, is a primary determinant for changes...
5.
Carvalho M, Medeiros M, Morais I, Lopes C, Balau A, Santos N, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674863
Malaria remains a major world public health problem, contributing to poverty and inequality. It is urgent to find new efficacious tools with few adverse effects. Malaria has selected red blood...
6.
Dardouri M, Bettencourt A, Martin V, Carvalho F, Colaco B, Gama A, et al.
Pharmaceutics
. 2022 Sep;
14(9).
PMID: 36145584
Silicone-based medical devices composed of polydimethylsiloxane (PDMS) are widely used all over the human body (e.g., urinary stents and catheters, central venous catheters stents) with extreme clinical success. Nevertheless, their...
7.
Dardouri M, Bettencourt A, Martin V, Carvalho F, Santos C, Monge N, et al.
Biomater Adv
. 2022 May;
134:112563.
PMID: 35525746
Controlling bacterial biofilm formation on silicone-based bloodstream catheters is of great concern to prevent related-infections. In this study, rhamnolipids (RLs), glycolipid biosurfactants, specifically a RLs mixture and the purified di-RL...
8.
Silva P, da Silva I, Sarmento M, Silva I, Carvalho F, Soveral G, et al.
Cells
. 2022 Apr;
11(8).
PMID: 35455986
Background: Aquaporins are membrane channels responsible for the bidirectional transfer of water and small non-charged solutes across cell membranes. AQP3 and AQP5 are overexpressed in pancreatic ductal adenocarcinoma, playing key...
9.
Morais I, Medeiros M, Carvalho M, Morello J, Teixeira S, Maciel S, et al.
Front Cell Infect Microbiol
. 2022 Apr;
12:840968.
PMID: 35372095
Mechanisms of malaria parasite interaction with its host red blood cell may provide potential targets for new antimalarial approaches. Pyruvate kinase deficiency has been associated with resistance to malaria in...
10.
Cruz T, Carvalho F, Matafome P, Soares R, Santos N, Travasso R, et al.
Biomedicines
. 2022 Jan;
10(1).
PMID: 35052737
Type 2 diabetes mellitus (T2DM) is a complex metabolic disease often associated with severe complications that may result in patient morbidity or death. One T2DM etiological agent is chronic hyperglycemia,...