Filipa C Simoes
Overview
Explore the profile of Filipa C Simoes including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
362
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Weinberger M, Simoes F, Gungoosingh T, Sauka-Spengler T, Riley P
Dev Cell
. 2024 Jan;
59(3):351-367.e6.
PMID: 38237592
Unlike the adult mammalian heart, which has limited regenerative capacity, the zebrafish heart fully regenerates following injury. Reactivation of cardiac developmental programs is considered key to successfully regenerating the heart,...
2.
Chong-Morrison V, Mayes S, Simoes F, Senanayake U, Carroll D, Riley P, et al.
Biol Open
. 2023 Jun;
12(6).
PMID: 37367831
Due to its genetic amenability coupled with advances in genome editing, zebrafish is an excellent model to examine the function of (epi)genomic elements. Here, we repurposed the Ac/Ds maize transposition...
3.
Marques I, Ernst A, Arora P, Vianin A, Hetke T, Sanz-Morejon A, et al.
Development
. 2022 May;
149(10).
PMID: 35621248
No abstract available.
4.
Simoes F, Riley P
Development
. 2022 May;
149(8).
PMID: 35502777
The immune system is fundamental to tissue homeostasis and is the first line of defense following infection, injury or disease. In the damaged heart, large numbers of immune cells are...
5.
Marques I, Ernst A, Arora P, Vianin A, Hetke T, Sanz-Morejon A, et al.
Development
. 2022 Mar;
149(6).
PMID: 35312773
During development, the heart grows by addition of progenitor cells to the poles of the primordial heart tube. In the zebrafish, Wilms tumor 1 transcription factor a (wt1a) and b...
6.
de Bakker D, Bouwman M, Dronkers E, Simoes F, Riley P, Goumans M, et al.
Development
. 2021 Sep;
148(19).
PMID: 34486669
Fibroblasts are activated to repair the heart following injury. Fibroblast activation in the mammalian heart leads to a permanent fibrotic scar that impairs cardiac function. In other organisms, such as...
7.
Weinberger M, Simoes F, Patient R, Sauka-Spengler T, Riley P
Dev Cell
. 2020 Feb;
52(5):574-590.e6.
PMID: 32084358
The epicardium is essential during cardiac development, homeostasis, and repair, and yet fundamental insights into its underlying cell biology, notably epicardium formation, lineage heterogeneity, and functional cross-talk with other cell...
8.
Simoes F, Cahill T, Kenyon A, Gavriouchkina D, Vieira J, Sun X, et al.
Nat Commun
. 2020 Feb;
11(1):600.
PMID: 32001677
Canonical roles for macrophages in mediating the fibrotic response after a heart attack include extracellular matrix turnover and activation of cardiac fibroblasts to initiate collagen deposition. Here we reveal that...
9.
Simoes F, Riley P
Development
. 2018 Mar;
145(7).
PMID: 29592950
The epicardium plays a key role during cardiac development, homeostasis and repair, and has thus emerged as a potential target in the treatment of cardiovascular disease. However, therapeutically manipulating the...
10.
Noseda M, Peterkin T, Simoes F, Patient R, Schneider M
Circ Res
. 2011 Jan;
108(1):129-52.
PMID: 21212394
Cardiac muscle creation during embryogenesis requires extracellular instructive signals that are regulated precisely in time and space, intersecting with intracellular genetic programs that confer or fashion the ability of the...