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Filip Cotra

Explore the profile of Filip Cotra including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Maroilley T, Rahit K, Chida A, Cotra F, Rodrigues Alves Barbosa V, Tarailo-Graovac M
G3 (Bethesda) . 2023 Aug; 13(11). PMID: 37585487
Genetic modifiers are variants modulating phenotypic outcomes of a primary detrimental variant. They contribute to rare diseases phenotypic variability, but their identification is challenging. Genetic screening with model organisms is...
2.
Cotra F, Maroilley T, Tarailo-Graovac M
MicroPubl Biol . 2023 Jun; 2023. PMID: 37313226
Balancers are primarily chromosomal rearrangements that allow lethal or sterile mutations to be stably maintained as heterozygotes. Strains with balanced lethal/sterile mutations are available at the Caenorhabditis Genetics Center. Such...
3.
Maroilley T, Flibotte S, Jean F, Rodrigues Alves Barbosa V, Galbraith A, Chida A, et al.
Genome Res . 2023 Jan; 33(1):154-167. PMID: 36617680
Genetic balancers in are complex variants that allow lethal or sterile mutations to be stably maintained in a heterozygous state by suppressing crossover events. Balancers constitute an invaluable tool in...