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Fernao C Braga

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Articles 39
Citations 319
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Recent Articles
1.
Mbiakop U, Gomes J, Padua R, Lemos V, Braga F, Cortes S
J Ethnopharmacol . 2023 Jan; 306:116164. PMID: 36681165
Ethnopharmacological Relevance: The endemic Brazilian medicinal plants of the genus Terminalia (Combretaceae), popularly known as capitão, comprising the similar species Terminalia phaeocarpa Eichler and Terminalia argentea, are traditionally and indistinguishably...
2.
Rocha M, Oliveira D, de Oliveira V, Zaidan I, Grossi L, Campana P, et al.
Planta Med . 2023 Jan; 89(7):718-728. PMID: 36626932
Gouty arthritis (GA) is an inflammatory arthritis triggered by the deposition of monosodium urate monohydrate (MSU) crystals, causing pain, inflammation, and joint damage. Several drugs are currently employed to manage...
3.
Freitas C, Lage D, Oliveira-da-Silva J, Costa R, Mendonca D, Martins V, et al.
Parasite . 2021 Apr; 28:38. PMID: 33851916
Current treatments of visceral leishmaniasis face limitations due to drug side effects and/or high cost, along with the emergence of parasite resistance. Novel and low-cost antileishmanial agents are therefore required....
4.
Caldeira A, Mbiakop U, Padua R, van de Venter M, Matsabisa M, Campana P, et al.
Food Chem . 2020 Dec; 345:128734. PMID: 33310563
Pequi fruit peels are an underexploited source of polyphenols. The anti-diabetic potential of an extract and fractions from the peels were evaluated in a panel of assays. The extract and...
5.
Freitas C, Oliveira-da-Silva J, Lage D, Costa R, Mendonca D, Martins V, et al.
Parasitol Res . 2020 Nov; 120(1):321-335. PMID: 33191446
Treatment for visceral leishmaniasis (VL) is hampered mainly by drug toxicity, their high cost, and parasite resistance. Drug development is a long and pricey process, and therefore, drug repositioning may...
6.
Moreira L, Feltrin C, Goncalves J, de Castro W, SimOes C, de Padua R, et al.
Biomed Pharmacother . 2020 Oct; 132:110900. PMID: 33113433
Hancornia speciosa is a medicinal plant with proven antihypertensive activity. The cyclitol l-(+)-bornesitol is the main constituent of its leaves and is a potent inhibitor of the angiotensin-converting enzyme. We...
7.
Rocha M, Campana P, Padua R, Souza Filho J, Ferreira D, Braga F
J Nat Prod . 2020 Jun; 83(6):1891-1898. PMID: 32484349
is an arborous species traditionally used in Brazil as an anti-inflammatory agent. Four new (3,3″)-linked biflavanone -methyl ethers, named ouratein A (), B (), C (), and D (), were...
8.
Munkert J, Gomes E, Marostica L, Cota B, Lopes C, Andrade S, et al.
ACS Omega . 2020 Jan; 4(26):22048-22056. PMID: 31891085
In recent years, cardiac glycosides (CGs) have been investigated as potential antiviral and anticancer drugs. Digitoxigenin (DIG) and other CGs have been shown to bind and inhibit Na/K-adenosinetriphosphatase (ATPase). Tumor...
9.
Moreira L, Silva G, Camara D, Padua R, Lemos V, Braga F, et al.
Biol Pharm Bull . 2019 Dec; 42(12):2076-2082. PMID: 31787722
The cyclitol bornesitol is the main constituent of the leaves from the antihypertensive medicinal plant Hancornia speciosa. This study aimed to investigate the ability of bornesitol to reduce blood pressure...
10.
Perez D, Galvao I, Athayde R, Rezende B, Vago J, Silva J, et al.
Eur J Immunol . 2019 Apr; 49(7):1038-1051. PMID: 30939218
Sphingosine-1-phosphate (S1P) is an important sphingolipid derived from plasma membrane and has a known role in productive phase of inflammation, but its role in neutrophil survival and resolution phase of...