Fernando Gianfrancesco
Overview
Explore the profile of Fernando Gianfrancesco including associated specialties, affiliations and a list of published articles.
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53
Citations
774
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Recent Articles
1.
Russo S, Scotto di Carlo F, Maurizi A, Fortunato G, Teti A, Licastro D, et al.
Bone Res
. 2023 Mar;
11(1):16.
PMID: 36918542
Paget's disease (PDB) is a late-onset bone remodeling disorder with a broad spectrum of symptoms and complications. One of the most aggressive forms is caused by the P937R mutation in...
2.
Scotto di Carlo F, Russo S, Muyas F, Mangini M, Garribba L, Pazzaglia L, et al.
Commun Biol
. 2023 Jan;
6(1):9.
PMID: 36599901
Profilin 1-encoded by PFN1-is a small actin-binding protein with a tumour suppressive role in various adenocarcinomas and pagetic osteosarcomas. However, its contribution to tumour development is not fully understood. Using...
3.
Russo S, Scotto di Carlo F, Gianfrancesco F
Front Cell Dev Biol
. 2022 Jun;
10:886305.
PMID: 35646939
Osteoclasts are highly specialized cells of the bone, with a unique apparatus responsible for resorption in the process of bone remodeling. They are derived from differentiation and fusion of hematopoietic...
4.
Gialluisi A, Reccia M, Modugno N, Nutile T, Lombardi A, Di Giovannantonio L, et al.
Mol Neurodegener
. 2021 Jun;
16(1):35.
PMID: 34148545
Background: Parkinson's disease (PD) is a neurodegenerative movement disorder affecting 1-5% of the general population for which neither effective cure nor early diagnostic tools are available that could tackle the...
5.
Kostrzewa M, Mahmoud A, Verde R, Scotto di Carlo F, Gianfrancesco F, Piscitelli F, et al.
Cells
. 2021 Jun;
10(5).
PMID: 34068882
Bone is a highly complex and metabolically active tissue undergoing a continuous remodeling process, which endures throughout life. A complex cell-signaling system that plays role in regulating different physiological processes,...
6.
Bortolini E, Pagani L, Oxilia G, Posth C, Fontana F, Badino F, et al.
Curr Biol
. 2021 Apr;
31(11):2484-2493.e7.
PMID: 33887180
Before the end of the Last Glacial Maximum (LGM, ∼16.5 ka ago) set in motion major shifts in human culture and population structure, a consistent change in lithic technology, material...
7.
Napolitano F, Terracciano C, Bruno G, De Blasiis P, Lombardi L, Gialluisi A, et al.
Neuropathol Appl Neurobiol
. 2021 Jan;
47(5):664-678.
PMID: 33393119
Background: Autophagic vacuolar myopathies (AVMs) are an emerging group of heterogeneous myopathies sharing histopathological features on muscle pathology, in which autophagic vacuoles are the pathognomonic morphologic hallmarks. Glycogen storage disease...
8.
Scotto di Carlo F, Whyte M, Gianfrancesco F
Cancer Lett
. 2020 Jun;
489:1-8.
PMID: 32502498
Giant cell tumor (GCT) is a bone-destructive benign neoplasm characterized by distinctive multinucleated osteoclast-like giant cells with osteolytic properties distributed among neoplastic stromal cells. GCT is locally aggressive with progressive...
9.
Scotto di Carlo F, Pazzaglia L, Mumm S, Benassi M, De Chiara A, Franchi A, et al.
J Bone Miner Res
. 2020 Feb;
35(10):1974-1980.
PMID: 32106343
Neoplastic transformation is a rare but serious complication of Paget's disease of bone (PDB), occurring in fewer than 1% of individuals with polyostotic disease. Their prognosis is poor, with less...
10.
Scotto di Carlo F, Pazzaglia L, Esposito T, Gianfrancesco F
J Bone Miner Res
. 2020 Jan;
35(8):1387-1398.
PMID: 31991009
Paget's disease of bone (PDB) is a late-onset disorder frequently caused by mutations in the SQSTM1 gene, leading to hyperactive osteoclasts and resulting in bone pain, deformities, and fractures. However,...