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Fella Hammachi

Explore the profile of Fella Hammachi including associated specialties, affiliations and a list of published articles. Areas
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Citations 97
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Recent Articles
1.
Sukparangsi W, Morganti E, Lowndes M, Mayeur H, Weisser M, Hammachi F, et al.
Nat Commun . 2022 Sep; 13(1):5537. PMID: 36130934
The support of pluripotent cells over time is an essential feature of development. In eutherian embryos, pluripotency is maintained from naïve states in peri-implantation to primed pluripotency at gastrulation. To...
2.
Dolt K, Hammachi F, Kunath T
Brain Pathol . 2017 Jun; 27(4):545-551. PMID: 28585381
Parkinson's disease (PD) is a common neurodegenerative condition affecting more than 8 million people worldwide. Although, the majority of PD cases are sporadic in nature, there are a growing number...
3.
Amorim I, Graham L, Carter R, Morton N, Hammachi F, Kunath T, et al.
J Cell Sci . 2017 Jan; 130(2):325-331. PMID: 28049716
α-Synuclein plays a central role in Parkinson's disease, where it contributes to the vulnerability of synapses to degeneration. However, the downstream mechanisms through which α-synuclein controls synaptic stability and degeneration...
4.
Livigni A, Peradziryi H, Sharov A, Chia G, Hammachi F, Portero Migueles R, et al.
Curr Biol . 2013 Nov; 23(22):2233-2244. PMID: 24210613
Background: The class V POU domain transcription factor Oct4 (Pou5f1) is a pivotal regulator of embryonic stem cell (ESC) self-renewal and reprogramming of somatic cells to induced pluripotent stem (iPS)...
5.
Hammachi F, Morrison G, Sharov A, Livigni A, Narayan S, Papapetrou E, et al.
Cell Rep . 2012 Jul; 1(2):99-109. PMID: 22832160
Oct4 is an essential regulator of pluripotency in vivo and in vitro in embryonic stem cells, as well as a key mediator of the reprogramming of somatic cells into induced...