Felke Steijns
Overview
Explore the profile of Felke Steijns including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
27
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Recent Articles
1.
Steijns F, Renard M, Vanhomwegen M, Vermassen P, Desloovere J, Raedt R, et al.
Int J Mol Sci
. 2020 Sep;
21(19).
PMID: 32987703
Patients with Marfan syndrome (MFS), a connective tissue disorder caused by pathogenic variants in the gene encoding the extracellular matrix protein fibrillin-1, have an increased prevalence of primary cardiomyopathy, arrhythmias,...
2.
Steijns F, Bracke N, Renard M, De Backer J, Sips P, Debunne N, et al.
Front Pharmacol
. 2020 Sep;
11:1336.
PMID: 32982746
Upregulation of the RAS-RAF-MEK-ERK-MAPK pathway is involved in the development of several human tumors, aortic aneurysms, atherosclerosis, and cardiomyopathy. Refametinib, a highly selective MEK-inhibitor, has already shown antineoplastic activity in...
3.
Steijns F, Toth M, Demolder A, Larsen L, Desloovere J, Renard M, et al.
Sensors (Basel)
. 2020 Jul;
20(14).
PMID: 32664419
Ambulatory electrocardiography (AECG) is a primary diagnostic tool in patients with potential arrhythmic disorders. To study the pathophysiological mechanisms of arrhythmic disorders, mouse models are widely implemented. The use of...
4.
Steijns F, van Hengel J, Sips P, De Backer J, Renard M
Histochem Cell Biol
. 2018 Jun;
150(3):271-280.
PMID: 29926163
Fibrillins are major constituents of microfibrils, which are essential components of the extracellular matrix of connective tissues where they contribute to the tissue homeostasis. Although it is known that microfibrils...
5.
Muino-Mosquera L, Steijns F, Audenaert T, Meerschaut I, De Paepe A, Steyaert W, et al.
Circ Genom Precis Med
. 2018 Jun;
11(6):e002039.
PMID: 29875124
Background: The introduction of next-generation sequencing techniques has substantially increased the identification of new genetic variants and hence the necessity of accurate variant interpretation. In 2015, the American College of...