Felix Sommer
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Explore the profile of Felix Sommer including associated specialties, affiliations and a list of published articles.
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52
Citations
3943
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Recent Articles
1.
Zeeb B, Weber-Stiehl S, Escudero-Hernandez C, Muller D, Maifeld A, Sommer F, et al.
Int J Mol Sci
. 2025 Mar;
26(5).
PMID: 40076765
Arterial hypertension is a major health challenge worldwide. Lifestyle factors including dietary NaCl increase the risk of hypertension. Pathophysiologically, the activation of the renin-angiotensin-aldosterone system and vascular remodeling, as well...
2.
Lopez-Agudelo V, Falk-Paulsen M, Bharti R, Rehman A, Sommer F, Wacker E, et al.
Gut Microbes
. 2024 Dec;
16(1):2429267.
PMID: 39620359
Throughout gestation, the female body undergoes a series of transformations, including profound alterations in intestinal microbial communities. Changes gradually increase toward the end of pregnancy and comprise reduced α-diversity of...
3.
Weber-Stiehl S, Taubenheim J, Jarke L, Rocken C, Schreiber S, Aden K, et al.
BMC Med
. 2024 Oct;
22(1):490.
PMID: 39444028
Background: Inflammation is characterized by a metabolic switch promoting glycolysis and lactate production. Hexokinases (HK) catalyze the first reaction of glycolysis and inhibition of epithelial HK2 protected from colitis in...
4.
Takaoka M, Zhao X, Lim H, Magnussen C, Ang O, Suffee N, et al.
Nature
. 2024 Sep;
634(8033):457-465.
PMID: 39231480
Hyperlipidaemia is a major risk factor of atherosclerotic cardiovascular disease (ASCVD). Risk of cardiovascular events depends on cumulative lifetime exposure to low-density lipoprotein cholesterol (LDL-C) and, independently, on the time...
5.
Johansson A, Subramani M, Yilmaz B, Nystrom E, Layunta E, Arike L, et al.
bioRxiv
. 2024 Jul;
PMID: 39005291
In the distal colon, mucus secreting goblet cells primarily confer protection from luminal microorganisms via generation of a sterile inner mucus layer barrier structure. Bacteria-sensing sentinel goblet cells provide a...
6.
Castrillon-Betancur J, Lopez-Agudelo V, Sommer N, Cleeves S, Bernardes J, Weber-Stiehl S, et al.
Antioxidants (Basel)
. 2023 Oct;
12(10).
PMID: 37891968
Reactive oxygen species (ROS) are highly reactive molecules formed from diatomic oxygen. They act as cellular signals, exert antibiotic activity towards invading microorganisms, but can also damage host cells. Dual...
7.
Pontarollo G, Kollar B, Mann A, Khuu M, Kiouptsi K, Bayer F, et al.
Nat Metab
. 2023 Sep;
5(9):1639.
PMID: 37697057
No abstract available.
8.
Pontarollo G, Kollar B, Mann A, Khuu M, Kiouptsi K, Bayer F, et al.
Nat Metab
. 2023 Jul;
5(7):1174-1187.
PMID: 37414930
The gut microbiota influences intestinal barrier integrity through mechanisms that are incompletely understood. Here we show that the commensal microbiota weakens the intestinal barrier by suppressing epithelial neuropilin-1 (NRP1) and...
9.
Effenberger M, Waschina S, Bronowski C, Sturm G, Tassiello O, Sommer F, et al.
Hepatol Commun
. 2023 Jun;
7(7).
PMID: 37314752
Background: HCC is the leading cause of cancer in chronic liver disease. A growing body of experimental mouse models supports the notion that gut-resident and liver-resident microbes control hepatic immune...
10.
Duan J, Matute J, Unger L, Hanley T, Schnell A, Lin X, et al.
Immunity
. 2023 Mar;
56(5):1115-1131.e9.
PMID: 36917985
Intestinal IL-17-producing T helper (Th17) cells are dependent on adherent microbes in the gut for their development. However, how microbial adherence to intestinal epithelial cells (IECs) promotes Th17 cell differentiation...