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Felix H Lam

Explore the profile of Felix H Lam including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 273
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Recent Articles
1.
Lam F, Turanli-Yildiz B, Liu D, Resch M, Fink G, Stephanopoulos G
Sci Adv . 2021 Jun; 7(26). PMID: 34172441
Lignocellulosic biomass remains unharnessed for the production of renewable fuels and chemicals due to challenges in deconstruction and the toxicity its hydrolysates pose to fermentation microorganisms. Here, we show in...
2.
Shaw A, Lam F, Hamilton M, Consiglio A, MacEwen K, Brevnova E, et al.
Science . 2016 Aug; 353(6299):583-6. PMID: 27493184
Microbial contamination is an obstacle to widespread production of advanced biofuels and chemicals. Current practices such as process sterilization or antibiotic dosage carry excess costs or encourage the development of...
3.
Lam F, Ghaderi A, Fink G, Stephanopoulos G
Science . 2014 Oct; 346(6205):71-5. PMID: 25278607
Ethanol toxicity in the yeast Saccharomyces cerevisiae limits titer and productivity in the industrial production of transportation bioethanol. We show that strengthening the opposing potassium and proton electrochemical membrane gradients...
4.
Lam F, Hartner F, Fink G, Stephanopoulos G
Methods Enzymol . 2010 Oct; 470:509-32. PMID: 20946823
As Saccharomyces cerevisiae is engineered further as a microbial factory for industrially relevant but potentially cytotoxic molecules such as ethanol, issues of cell viability arise that threaten to place a...
5.
Lam F, Steger D, OShea E
Nature . 2008 Apr; 453(7192):246-50. PMID: 18418379
Chromatin influences gene expression by restricting access of DNA binding proteins to their cognate sites in the genome. Large-scale characterization of nucleosome positioning in Saccharomyces cerevisiae has revealed a stereotyped...