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Felix Gruber

Explore the profile of Felix Gruber including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 74
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Recent Articles
1.
Bologheanu R, Bilir A, Kapral L, Gruber F, Kimberger O
JAMA Netw Open . 2025 Feb; 8(2):e2460794. PMID: 39976966
Importance: New persistent opioid use after surgery is contributing to the opioid crisis affecting the US, and interventions to limit postoperative opioid prescriptions have been proposed to mitigate the opioid-related...
2.
Wurm R, Klotz S, Erber A, Gruber F, Leitner S, Reichardt B, et al.
JAMA Neurol . 2025 Jan; 82(2):185-192. PMID: 39786417
Importance: Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare, rapidly progressive and fatal neurodegenerative disease. Definite sCJD diagnosis can only be made post mortem, and little is known about the prodromal...
3.
Liang J, Lambrecht M, Arenzana T, Aubert-Nicol S, Bao L, Broccatelli F, et al.
ACS Med Chem Lett . 2024 Jun; 15(6):864-872. PMID: 38894924
We were attracted to the therapeutic potential of inhibiting Casitas B-lineage lymphoma proto-oncogene-b (Cbl-b), a RING E3 ligase that plays a critical role in regulating the activation of T cells....
4.
Massmeyer O, Gunkel R, Glowatzki J, Klement P, Ojaghi Dogahe B, Kachel S, et al.
Small . 2024 May; 20(37):e2402155. PMID: 38795001
Two-dimensional (2D) materials exhibit the potential to transform semiconductor technology. Their rich compositional and stacking varieties allow tailoring materials' properties toward device applications. Monolayer to multilayer gallium sulfide (GaS) with...
5.
Gruber F, McDonagh A, Rose V, Hunter J, Guasch L, Martin R, et al.
Angew Chem Int Ed Engl . 2024 Feb; 63(12):e202319836. PMID: 38330151
DNA encoded library (DEL) synthesis represents a convenient means to produce, annotate and store large collections of compounds in a small volume. While DELs are well suited for drug discovery...
6.
Widemann M, Krug D, Massmeyer O, Gruber F, Beyer A, Volz K
Small Methods . 2023 Dec; 8(7):e2301079. PMID: 38133519
In situ transmission electron microscopy (TEM) observations of the metal-organic vapor phase epitaxy (MOVPE) growth promise to enhance the understanding of this complex process. However, a new experimental approach is...
7.
Weisshaar S, Litschauer B, Reichardt B, Gruber F, Leitner S, Sibinovic S, et al.
Rheumatol Int . 2022 May; 42(9):1597-1603. PMID: 35589988
Patients with hyperuricemia and gout are at an increased risk for cardiovascular (CV) disease. Inhibition of the xanthine oxidase with allopurinol or febuxostat have become the mainstay for urate lowering...
8.
Satz A, Cai J, Chen Y, Goodnow R, Gruber F, Kowalczyk A, et al.
Bioconjug Chem . 2016 Sep; 27(10):2580. PMID: 27643718
No abstract available.
9.
Satz A, Cai J, Chen Y, Goodnow R, Gruber F, Kowalczyk A, et al.
Bioconjug Chem . 2015 May; 26(8):1623-32. PMID: 26024553
Complex mixtures of DNA encoded small molecules may be readily interrogated via high-throughput sequencing. These DNA encoded libraries (DELs) are commonly used to discover molecules that interact with pharmaceutically relevant...