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Felix Gremse

Explore the profile of Felix Gremse including associated specialties, affiliations and a list of published articles. Areas
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Articles 115
Citations 2502
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Recent Articles
1.
May J, Moss J, Mueller F, Golombek S, Biancacci I, Rizzo L, et al.
Nat Biomed Eng . 2024 Apr; 8(11):1366-1378. PMID: 38589466
The clinical prospects of cancer nanomedicines depend on effective patient stratification. Here we report the identification of predictive biomarkers of the accumulation of nanomedicines in tumour tissue. By using supervised...
2.
Schraven S, Bruck R, Rosenhain S, Lemainque T, Heines D, Noormohammadian H, et al.
Invest Radiol . 2023 Dec; 59(7):504-512. PMID: 38038691
Objectives: Optical fluorescence imaging can track the biodistribution of fluorophore-labeled drugs, nanoparticles, and antibodies longitudinally. In hybrid computed tomography-fluorescence tomography (CT-FLT), CT provides the anatomical information to generate scattering and...
3.
Mockel D, Bartneck M, Niemietz P, Wagner M, Ehling J, Rama E, et al.
J Control Release . 2023 Nov; 365:358-368. PMID: 38016488
Blood vessel functionality is crucial for efficient tumor-targeted drug delivery. Heterogeneous distribution and perfusion of angiogenic blood vessels contribute to suboptimal accumulation of (nano-) therapeutics in tumors and metastases. To...
4.
Thamm M, Jeffery J, Zhang Y, Smith B, Marchant S, Kiessling F, et al.
J Vis Exp . 2023 Nov; (200). PMID: 37955389
Integrated preclinical multimodal imaging systems, such as X-ray computed tomography (CT) combined with positron emission tomography (PET) or magnetic resonance imaging (MRI) combined with PET, are widely available and typically...
5.
Mueller-Diesing F, Lederle W, Rix A, Koletnik S, Doleschel D, Snelting M, et al.
Int J Mol Sci . 2023 Apr; 24(8). PMID: 37108226
Acetylsalicylic acid (ASA) is a well-established drug for heart attack and stroke prophylaxis. Furthermore, numerous studies have reported an anti-carcinogenic effect, but its exact mechanism is still unknown. Here, we...
6.
Van Gaalen K, Quinn C, Weiler M, Gremse F, Benn F, McHugh P, et al.
Bioact Mater . 2023 Mar; 26:437-451. PMID: 36993789
In this study, the influence of a plasma electrolytic oxidation (PEO) surface treatment on a medical-grade WE43-based magnesium alloy is examined through an experimental and computational framework that considers the...
7.
Schraven S, Rosenhain S, Brueck R, Wiechmann T, Pola R, Etrych T, et al.
Nanomedicine . 2023 Jan; 48:102650. PMID: 36623712
Biodistribution analyses of nanocarriers are often performed with optical imaging. Though dye tags can interact with transporters, e.g., organic anion transporting polypeptides (OATPs), their influence on biodistribution was hardly studied....
8.
Tavares A, Mezzanotte L, McDougald W, Bernsen M, Vanhove C, Aswendt M, et al.
Mol Imaging Biol . 2022 Dec; 25(3):560-568. PMID: 36482032
Purpose: To support acquisition of accurate, reproducible and high-quality preclinical imaging data, various standardisation resources have been developed over the years. However, it is unclear the impact of those efforts...
9.
Kubo Y, Gonzalez J, Beckmann R, Weiler M, Pahlavani H, Saldivar M, et al.
BMC Musculoskelet Disord . 2022 Nov; 23(1):1015. PMID: 36434613
Background: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a crucial transcription factor for cellular redox homeostasis. The association of Nrf2 with elderly female osteoporotic has yet to be fully...
10.
Mohlhenrich S, Kniha K, Heitzer M, Magnuska Z, Hermanns-Sachweh B, Gremse F, et al.
Head Face Med . 2022 Nov; 18(1):33. PMID: 36357936
Background: The evaluation of bone remodelling and dental root resorption can be performed by histological techniques or micro-computed tomography (micro-CT). The present study aimed to evaluate the relationship between these...