Felix Grassmann
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Explore the profile of Felix Grassmann including associated specialties, affiliations and a list of published articles.
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85
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2521
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Recent Articles
1.
Mihov M, Shoctor H, Douglas A, Hay D, OShaughnessy P, Iredale J, et al.
EBioMedicine
. 2025 Mar;
:105590.
PMID: 40074595
Background: Maternal smoking and foetal exposure to nicotine and other harmful chemicals in utero remains a serious public health issue with little knowledge about the underlying genetics and consequences of...
2.
Papadam A, Lionikas A, Grassmann F
Aging Cell
. 2025 Jan;
:e14473.
PMID: 39757747
Age-related macular degeneration (AMD) is a progressive disorder and the leading cause of central vision loss. Age is the most important risk factor, followed by genetics and smoking. However, ageing...
3.
Luo J, le Cessie S, Willems van Dijk K, Hagg S, Grassmann F, van Heemst D, et al.
Mitochondrion
. 2024 Nov;
80:101991.
PMID: 39592086
Background: Low leukocyte mitochondrial DNA (mtDNA) abundance has been associated with a higher risk of atherosclerotic cardiovascular disease, but through unclear mechanisms. We aimed to investigate whether low mtDNA abundance...
4.
Zanti M, OMahony D, Parsons M, Dorling L, Dennis J, Boddicker N, et al.
medRxiv
. 2024 Sep;
PMID: 39281752
Clinical genetic testing identifies variants causal for hereditary cancer, information that is used for risk assessment and clinical management. Unfortunately, some variants identified are of uncertain clinical significance (VUS), complicating...
5.
Davidson A, Michailidou K, Parsons M, Fortuno C, Bolla M, Wang Q, et al.
Am J Hum Genet
. 2024 Aug;
111(9):2059-2069.
PMID: 39096911
Co-observation of a gene variant with a pathogenic variant in another gene that explains the disease presentation has been designated as evidence against pathogenicity for commonly used variant classification guidelines....
6.
Polyunsaturated Fatty Acid - mediated Cellular Rejuvenation for Reversing Age-related Vision Decline
Gao F, Tom E, Rydz C, Cho W, Kolesnikov A, Sha Y, et al.
bioRxiv
. 2024 Jul;
PMID: 39005302
The retina is uniquely enriched in polyunsaturated fatty acids (PUFAs), which are primarily localized in cell membranes, where they govern membrane biophysical properties such as diffusion, permeability, domain formation, and...
7.
Leeson-Payne A, Iyinikkel J, Malcolm C, Lam B, Sommer N, Dowsett G, et al.
Cell Metab
. 2024 Apr;
36(5):1076-1087.e4.
PMID: 38653246
Approximately 1 in 4 people worldwide have non-alcoholic fatty liver disease (NAFLD); however, there are currently no medications to treat this condition. This study investigated the role of adiposity-associated orphan...
8.
Xiao Q, Mao X, Ploner A, Grassmann F, Rodriguez J, Eriksson M, et al.
J Natl Cancer Inst
. 2024 Feb;
116(6):911-919.
PMID: 38366028
Background: Associations between germline alterations in women and cancer risks among their relatives are largely unknown. Methods: We identified women from 2 Swedish cohorts Karolinska Mammography Project for Risk Prediction...
9.
Pfaller A, Kaplan L, Carido M, Grassmann F, Diaz-Lezama N, Ghaseminejad F, et al.
J Neuroinflammation
. 2024 Jan;
21(1):33.
PMID: 38273366
Diabetic retinopathy (DR) is considered a primarily microvascular complication of diabetes. Müller glia cells are at the centre of the retinal neurovascular unit and play a critical role in DR....
10.
Rodriguez J, Grassmann F, Xiao Q, Eriksson M, Mao X, Bajalica-Lagercrantz S, et al.
JAMA Oncol
. 2024 Jan;
10(3):372-379.
PMID: 38270937
Importance: Breast cancers (BCs) diagnosed between 2 screening examinations are called interval cancers (ICs), and they have worse clinicopathological characteristics and poorer prognosis than screen-detected cancers (SDCs). However, the association...