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Felix Geist

Explore the profile of Felix Geist including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 147
Followers 0
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Recent Articles
1.
Ramler J, Geist F, Mihm C, Lubczyk L, Reith S, Herok C, et al.
Chemistry . 2024 Nov; 31(3):e202403253. PMID: 39498538
A series of dibenzobismepinyl (CHBi) substituted transition metal complexes of the type [(CHBi)M(CO)(L)] (M=Mn, Co, Fe) was prepared in salt elimination reactions from a halobismepine and sodium metallates. Irradiation of...
2.
Simard M, Cabrera-Galvez C, Viteri S, Geist F, Reischmann N, Zuhlsdorf M, et al.
Neoplasia . 2024 Oct; 57:101063. PMID: 39366215
MET inhibitors have demonstrated efficacy in treating patients with non-small cell lung cancer (NSCLC) harboring METex14 skipping alterations. Advancements in spatial profiling technologies have unveiled the complex dynamics of the...
3.
Vinik Y, Maimon A, Raj H, Dubey V, Geist F, Wienke D, et al.
iScience . 2024 Sep; 27(9):110859. PMID: 39310772
Identification of promising targets for cancer therapy is a global effort in precision medicine. Here, we describe a computational pipeline integrating transcriptomic and vulnerability responses to cell-death inducing drugs, to...
4.
Kreis J, Aybey B, Geist F, Brors B, Staub E
Cancer Res Commun . 2024 Feb; 4(2):516-529. PMID: 38349551
Significance: Cancer self-renewal and migratory abilities are often characterized via gene module expression profiles, also called EMT or stemness gene expression signatures. Using published clinical tumor samples, cancer cell lines,...
5.
Braune E, Geist F, Tang X, Kalari K, Boughey J, Wang L, et al.
Breast Cancer Res . 2024 Jan; 26(1):4. PMID: 38172915
Background: Dysregulated Notch signalling contributes to breast cancer development and progression, but validated tools to measure the level of Notch signalling in breast cancer subtypes and in response to systemic...
6.
Kreis J, Nedic B, Mazur J, Urban M, Schelhorn S, Grombacher T, et al.
Neoplasia . 2021 Sep; 23(11):1069-1077. PMID: 34583245
Gene expression signatures have proven their potential to characterize important cancer phenomena like oncogenic signaling pathway activities, cellular origins of tumors, or immune cell infiltration into tumor tissues. Large collections...
7.
Ramler J, Fantuzzi F, Geist F, Hanft A, Braunschweig H, Engels B, et al.
Angew Chem Int Ed Engl . 2021 Aug; 60(46):24388-24394. PMID: 34378855
The isolation of simple, fundamentally important, and highly reactive organometallic compounds remains among the most challenging tasks in synthetic chemistry. The detailed characterization of such compounds is key to the...
8.
Hanft A, Rottschafer D, Wieprecht N, Geist F, Radacki K, Lichtenberg C
Chemistry . 2021 Jul; 27(57):14250-14262. PMID: 34314083
Aminotroponiminate (ATI) ligands are a versatile class of redox-active and potentially cooperative ligands with a rich coordination chemistry that have consequently found a wide range of applications in synthesis and...
9.
Schell C, Sabass B, Helmstaedter M, Geist F, Abed A, Yasuda-Yamahara M, et al.
Dev Cell . 2018 Dec; 47(6):741-757.e8. PMID: 30503751
Podocytes, highly specialized epithelial cells, build the outer part of the kidney filtration barrier and withstand high mechanical forces through a complex network of cellular protrusions. Here, we show that...
10.
Lorentzen A, Becker P, Kosla J, Saini M, Weidele K, Ronchi P, et al.
Nat Commun . 2018 Mar; 9(1):887. PMID: 29491397
Dynamic polarisation of tumour cells is essential for metastasis. While the role of polarisation during dedifferentiation and migration is well established, polarisation of metastasising tumour cells during phases of detachment...