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Felipe V Gomes

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Articles 74
Citations 1274
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Recent Articles
1.
Pedrazzi J, Silva-Amaral D, Issy A, Gomes F, Crippa J, Guimaraes F, et al.
Pharmacol Biochem Behav . 2024 Sep; 245():173879. PMID: 39305939
Individuals with schizophrenia (SCZ) often present sensorimotor gating impairments that can be investigated by the prepulse inhibition test (PPI). PPI disruption can be mimicked experimentally with psychostimulants such as amphetamine...
2.
Santos-Silva T, Souza B, Colodete D, Campos L, Lima T, Guimaraes F, et al.
Int J Neuropsychopharmacol . 2024 Sep; 27(10). PMID: 39276147
Background: Stress has become a common public health concern, contributing to the rising prevalence of psychiatric disorders. Understanding the impact of stress considering critical variables, such as age, sex, and...
3.
Souza A, Freitas I, Sharmin D, Cook J, Guimaraes F, Gomes F
Autism Res . 2024 Aug; 17(8):1534-1544. PMID: 39169698
Autism spectrum disorders (ASDs) are characterized by core behavioral symptoms in the domains of sociability, language/communication, and repetitive or stereotyped behaviors. Deficits in the prefrontal and hippocampal excitatory/inhibitory balance due...
4.
Colodete D, Grace A, Guimaraes F, Gomes F
Biol Psychiatry Glob Open Sci . 2024 Aug; 4(5):100338. PMID: 39099729
Background: Psychiatric disorders often emerge during late adolescence/early adulthood, a period with increased susceptibility to socioenvironmental factors that coincides with incomplete parvalbumin interneuron (PVI) development. Stress during this period causes...
5.
Fabris D, Lisboa J, Guimaraes F, Gomes F
Int Rev Neurobiol . 2024 Jul; 177:295-317. PMID: 39029989
Cannabidiol (CBD) is a major phytocannabinoid in the Cannabis sativa plant. In contrast to Δ-tetrahydrocannabinol (THC), CBD does not produce the typical psychotomimetic effects of the plant. In addition, CBD...
6.
Lisboa J, Costa O, Pakes G, Colodete D, Gomes F
Schizophr Res . 2024 Jul; 271:100-109. PMID: 39018984
Background: The onset of schizophrenia is concurrent with multiple key processes of brain development, such as the maturation of inhibitory networks. Some of these processes are proposed to depend on...
7.
Uliana D, Lisboa J, Gomes F, Grace A
Biochem Pharmacol . 2024 May; 228:116298. PMID: 38782077
The intricate balance between excitation and inhibition (E/I) in the brain plays a crucial role in normative information processing. Dysfunctions in the E/I balance have been implicated in various psychiatric...
8.
Pagliusi Jr M, Amorim-Marques A, Lobo M, Guimaraes F, Lisboa S, Gomes F
Pain . 2024 Apr; 165(8):1814-1823. PMID: 38661577
The rostral ventromedial medulla (RVM) is a crucial structure in the descending pain modulatory system, playing a key role as a relay for both the facilitation and inhibition of pain....
9.
Santos-Silva T, Lopes C, Hazar Ulgen D, Guimaraes D, Guimaraes F, Alberici L, et al.
Schizophr Bull . 2024 Mar; 51(2):501-512. PMID: 38525594
Background And Hypothesis: Redox dysregulation has been proposed as a convergent point of childhood trauma and the emergence of psychiatric disorders, such as schizophrenia (SCZ). A critical region particularly vulnerable...
10.
Santos-Silva T, Colodete D, Lisboa J, Freitas I, Lopes C, Hadera V, et al.
Basic Clin Pharmacol Toxicol . 2024 Mar; 134(5):614-628. PMID: 38426366
The brain extracellular matrix (ECM) has garnered increasing attention as a fundamental component of brain function in a predominantly "neuron-centric" paradigm. Particularly, the perineuronal nets (PNNs), a specialized net-like structure...