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Felipe Takaesu

Explore the profile of Felipe Takaesu including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 137
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Recent Articles
1.
Forghani P, Liu W, Wang Z, Ling Z, Takaesu F, Yang E, et al.
Biomaterials . 2025 Jan; 317:123080. PMID: 39809079
Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) possess tremendous advantage for cardiac regeneration. However, cell survival is challenging upon cell transplantation. Since microgravity can profoundly affect cellular properties,...
2.
Kelly J, Hu Z, Takaesu F, Watanabe T, Storrs J, Blais B, et al.
JTCVS Open . 2024 Nov; 21:268-278. PMID: 39534321
Objectives: Our goal was to conduct a hemodynamic analysis of a novel animal model of Fontan physiology. Poor late-term outcomes in Fontan patients are believed to arise from Fontan-induced hemodynamics,...
3.
Lee J, Gleizes A, Janto N, Appell L, Sun S, Takaesu F, et al.
Development . 2024 Nov; 151(23). PMID: 39503201
Progenitors and mature cells can maintain the intestinal epithelium by dedifferentiation and facultative intestinal stem cell (fISC) function when active ISCs (aISCs) are lost to damage. Here, we modeled fISC...
4.
Lee J, Gleizes A, Takaesu F, Webster S, Hailstock T, Barker N, et al.
bioRxiv . 2024 Apr; PMID: 38645040
Progenitors and mature cells can maintain the intestinal epithelium by dedifferentiation and facultative intestinal stem cell (fISC) function when active ISCs (aISCs) are lost to damage. Here, we sought to...
5.
Rochman N, Raciti D, Takaesu F, Sun S
Eng Rep . 2024 Apr; 2(5). PMID: 38586583
Growing interest in renewable energy continues to motivate new work on microbial biohydrogen production and in particular utilizing a well-studied, facultative anaerobe. Here we characterize, for the first time the...
6.
Bheri S, Park H, Hoffman J, Takaesu F, Davis M
Adv Biol (Weinh) . 2023 Dec; 8(3):e2300462. PMID: 38143286
Cell therapies involving c-kit+ progenitor cells (CPCs) and mesenchymal stem cells (MSCs) have been actively studied for cardiac repair. The benefits of such therapies have more recently been attributed to...
7.
Bheri S, Brown M, Park H, Brazhkina O, Takaesu F, Davis M
ACS Nano . 2023 Sep; 17(20):19613-19624. PMID: 37715735
Small extracellular vesicles (sEVs) are promising for cell-based cardiac repair after myocardial infarction. These sEVs encapsulate potent cargo, including microRNAs (miRs), within a bilayer membrane that aids sEV uptake when...
8.
Li W, Berlinicke C, Huang Y, Giera S, McGrath A, Fang W, et al.
iScience . 2023 Feb; 26(3):106156. PMID: 36852281
Promoting myelination capacity of endogenous oligodendrocyte precursor cells (OPCs) is a promising therapeutic approach for CNS demyelinating disorders such as Multiple Sclerosis (MS). To aid in the discovery of myelination-promoting...
9.
Park H, Kelly J, Hoffman J, Takaesu F, Schwartzman W, Ulziibayar A, et al.
Extracell Vesicle . 2022 Nov; 1. PMID: 36330420
Patients with single ventricle heart defects requires a series of staged open-heart procedures, termed Fontan palliation. However, while lifesaving, these operations are associated with significant morbidity and early mortality. The...
10.
Zhang P, Zhang S, Li W, Keuthan C, Li S, Takaesu F, et al.
EBioMedicine . 2022 Aug; 83:104225. PMID: 36030648
Background: Though case fatality rate (CFR) is widely used to reflect COVID-19 fatality risk, its use is limited by large temporal and spatial variation. Hospital mortality rate (HMR) is also...