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Felipe Rojas-Rodriguez

Explore the profile of Felipe Rojas-Rodriguez including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Rojas-Rodriguez F, Schmidt M, Canisius S
Bioinform Adv . 2024 May; 4(1):vbae073. PMID: 38808071
Motivation: Most cancer driver gene identification tools have been developed for whole-exome sequencing data. Targeted sequencing is a popular alternative to whole-exome sequencing for large cancer studies due to its...
2.
Azkanaz M, Corominas-Murtra B, Ellenbroek S, Bruens L, Webb A, Laskaris D, et al.
Nature . 2022 Jul; 607(7919):548-554. PMID: 35831497
The morphology and functionality of the epithelial lining differ along the intestinal tract, but tissue renewal at all sites is driven by stem cells at the base of crypts. Whether...
3.
Rojas-Rodriguez F, Morantes C, Pinzon A, Barreto G, Cabezas R, Marino-Ramirez L, et al.
Open Bioinforma J . 2021 Apr; 13:1-14. PMID: 33927788
Aims: Present a novel machine learning computational strategy to predict the neuroprotection potential of nicotine analogs acting over the behavior of unpaired signaling pathways in Parkinson's disease. Background: Dopaminergic replacement...
4.
Puentes-Tellez M, Sanchez O, Rojas-Rodriguez F, Benincore-Florez E, Barbosa H, Almeciga Diaz C
Gene . 2021 Feb; 780:145527. PMID: 33636292
Mucopolysaccharidosis type IVA (MPS IVA) is a lysosomal storage disease produced by the deficiency of the N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme, leading to glycosaminoglycans (GAGs) accumulation. Since currently available treatments remain...
5.
Castellanos D, Martin-Jimenez C, Rojas-Rodriguez F, Barreto G, Gonzalez J
Front Neuroendocrinol . 2021 Jan; 61:100899. PMID: 33450200
Lipids are essential for cellular functioning considering their role in membrane composition, signaling, and energy metabolism. The brain is the second most abundant organ in terms of lipid concentration and...
6.
Becerra G, Rojas-Rodriguez F, Ramirez D, Loaiza A, Tobar-Tosse F, Mejia S, et al.
Comput Biol Chem . 2020 May; 86:107266. PMID: 32388154
As the mechanism of interaction between nicotinic receptors with nicotine analogs is not yet fully understood, information at molecular level obtained from computational calculations is needed. In this sense, this...