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Feizhou Lu

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Articles 64
Citations 554
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Recent Articles
1.
Gong Z, Chen Z, Li D, Lu X, Wu J, Sun H, et al.
J Nanobiotechnology . 2025 Jan; 23(1):29. PMID: 39833803
Background: Spinal cord injury (SCI) treatment remains a formidable challenge, as current therapeutic approaches provide only marginal relief and fail to reverse the underlying tissue damage. This study aims to...
2.
Li D, Liu S, Lu X, Gong Z, Wang H, Xia X, et al.
CNS Neurosci Ther . 2024 Dec; 30(12):e70130. PMID: 39648661
Background: The treatment of spinal cord injury (SCI) is usually ineffective, because neuroinflammatory secondary injury is an important cause of the continuous development of spinal cord injury, and microglial pyroptosis...
3.
Lin Z, Xu G, Lu X, Wang H, Lu F, Xia X, et al.
Aging Cell . 2024 Nov; :e14440. PMID: 39610146
Mitochondrial homeostasis plays a crucial role in degenerative joint diseases, including cartilaginous endplate (CEP) degeneration. To date, research into mitochondrial dynamics in IVDD is at an early stage. Since Piezo1...
4.
Lu X, Li D, Lin Z, Gao T, Gong Z, Zhang Y, et al.
Aging Cell . 2024 May; 23(9):e14210. PMID: 38783692
The nucleus pulposus is in a hypoxic environment in the human body, and when intervertebral disc degeneration (IVDD) occurs, the hypoxic environment is disrupted. Nucleus pulposus cell (NPC) ferroptosis is...
5.
Sun C, Xu G, Wang H, Nie C, Xu G, Liu D, et al.
Clin Spine Surg . 2024 Apr; 37(10):E415-E423. PMID: 38637922
Study Design: Observational study. Objective: To assess the reproducibility and reliability of the system. Background: The Huashan radiologic classification system for cervical spinal cord injury without fracture and dislocation (CSCIWFD)...
6.
Li D, Lu X, Gong Z, Liu S, Xu G, Wang H, et al.
Eur Spine J . 2024 Apr; 33(8):3230-3241. PMID: 38602526
Objective: The traditional VBQ scoring method may lead to overestimation due to the concentration of intravertebral fat and vascular structures in the posterior half of vertebral bodies, potentially resulting in...
7.
Xu G, Lu X, Liu S, Zhang Y, Xu S, Ma X, et al.
Stem Cell Rev Rep . 2023 Aug; 19(7):2465-2480. PMID: 37528254
Bone marrow mesenchymal stem cell derived exosomes (BMSC-exos) are a crucial means of intercellular communication and can regulate a range of biological processes by reducing inflammation, decreasing apoptosis and promoting...
8.
Chen Z, Song J, Xie L, Xu G, Zheng C, Xia X, et al.
Cell Death Differ . 2023 Jul; 30(8):1957-1972. PMID: 37438603
Circular RNAs (circRNAs) are a class of noncoding RNAs that have been found to be involved in intervertebral disc degeneration (IVDD) progression, and N6-methyladenosine (m6A) broadly exists in circRNAs. Here,...
9.
Li D, Lu X, Xu G, Liu S, Gong Z, Lu F, et al.
CNS Neurosci Ther . 2023 Mar; 29(7):1923-1939. PMID: 36942513
Background: Spinal cord injury (SCI) is a highly disabling condition in spinal surgery that leads to neuronal damage and secondary inflammation. Ferroptosis is a non-apoptotic type of cell death that...
10.
Lu X, Xu G, Lin Z, Song J, Zhang Y, Wang H, et al.
Oxid Med Cell Longev . 2023 Jan; 2023:3626091. PMID: 36647429
Intervertebral disc degeneration (IVDD) is one of the main causes of low back pain, which brings heavy burdens to individuals and society. The mechanism of IVDD is complex and diverse....