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Federico Kalinec

Explore the profile of Federico Kalinec including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 705
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Recent Articles
1.
Palbrink A, Kopietz F, Moren B, In t Zandt R, Kalinec F, Stenkula K, et al.
BMJ Open Diabetes Res Care . 2020 Apr; 8(1). PMID: 32238362
Objective: The mechanisms underlying the association between diabetes and inner ear dysfunction are not known yet. The aim of the present study is to evaluate the impact of obesity/insulin resistance...
2.
Kalinec G, Gao L, Cohn W, Whitelegge J, Faull K, Kalinec F
Front Cell Neurosci . 2019 Dec; 13:530. PMID: 31849615
Drug- and noise-related hearing loss are both associated with inflammatory responses in the inner ear. We propose that intracochlear delivery of a combination of pro-resolving mediators, specialized proteins and lipids...
3.
Kalinec G, Cohn W, Whitelegge J, Faull K, Kalinec F
Ann Otol Rhinol Laryngol . 2019 May; 128(6_suppl):52S-60S. PMID: 31092033
Objectives: Isolate, purify, and characterize extracellular vesicles (EVs) obtained from auditory HEI-OC1 cells, and evaluate their suitability for intracochlear transport and delivery of pharmacological drugs and/or pro-resolution mediators of acute...
4.
Pierstorff E, Yang W, Chen Y, Cheung S, Kalinec F, Slattery W
Int J Pediatr Otorhinolaryngol . 2019 Mar; 121:157-163. PMID: 30913504
Objective: Cisplatin is a chemotherapeutic drug known to induce hearing loss. Although corticosteroids may help to mitigate the ototoxic side effects of cisplatin, there are complications associated with their systemic...
5.
Pierstorff E, Chen S, Chaparro M, Cortez Jr J, Chen Y, Ryu S, et al.
Otol Neurotol . 2018 Sep; 39(9):1195-1202. PMID: 30199502
Objective: Investigate a new polymer-based drug coating suitability for safe intracochlear delivery and ability to maintain long-term physiologically active levels of the corticosteroid fluticasone propionate. Study Design: In vitro dissolution...
6.
Kalinec G, Lomberk G, Urrutia R, Kalinec F
Front Cell Neurosci . 2017 Jul; 11:192. PMID: 28736517
A significant number of studies support the idea that inflammatory responses are intimately associated with drug-, noise- and age-related hearing loss (DRHL, NRHL and ARHL). Consequently, several clinical strategies aimed...
7.
Kalinec G, Park C, Thein P, Kalinec F
J Vis Exp . 2016 Sep; (115). PMID: 27684094
HEI-OC1 is one of the few mouse auditory cell lines available for research purposes. Originally proposed as an in vitro system for screening of ototoxic drugs, these cells have been...
8.
Kalinec G, Thein P, Park C, Kalinec F
Hear Res . 2016 Mar; 335:105-117. PMID: 26930622
The House Ear Institute-Organ of Corti 1 (HEI-OC1) is one of the few, and arguable the most used, mouse auditory cell line available for research purposes. Originally proposed as an...
9.
Park C, Thein P, Kalinec G, Kalinec F
Hear Res . 2016 Feb; 335:9-17. PMID: 26854618
The House Ear Institute-Organ of Corti 1 (HEI-OC1) is a mouse auditory cell line that endogenously express, among other several markers of cochlear hair cells, the motor protein prestin (SLC26A5)....
10.
Urrutia R, Kalinec F
Hear Res . 2015 May; 330(Pt A):26-38. PMID: 25987503
The current review article seeks to extend our understanding on the role of lipid droplets within the organ of Corti. In addition to presenting an overview of the current information...