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» Authors » Federica Sentinelli

Federica Sentinelli

Explore the profile of Federica Sentinelli including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 35
Citations 447
Followers 0
Related Specialties
Endocrinology
Biochemistry
Molecular Biology
Top 10 Co-Authors
Marco Giorgio Baroni
Stefano Romeo
Michela Incani
Ilaria Barchetta
Efisio Cossu
Marco G Baroni
Maria Gisella Cavallo
Frida Leonetti
Laura Bertoccini
Flavia Agata Cimini
Published In
Int J Mol Sci
Diabetes Metab Res Rev
Nutr Metab Cardiovasc Dis
Lipids Health Dis
Endocr Res
Affiliations
Soon will be listed here.
Recent Articles
1.
Association Between Active DNA Demethylation and Liver Fibrosis in Individuals with Metabolic-Associated Steatotic Liver Disease (MASLD)
Barchetta I, Zampieri M, Cimini F, Dule S, Sentinelli F, Passarella G, et al.
Int J Mol Sci . 2025 Feb; 26(3). PMID: 39941038
Metabolic-associated steatotic liver disease (MASLD) represents the most common chronic hepatopathy worldwide and an independent risk factor for cardiovascular disease and mortality, particularly when liver fibrosis occurs. Epigenetic alterations, such...
2.
Circulating Proneurotensin Levels Predict Impaired Bone Mineralisation in Postmenopausal Women With Type 2 Diabetes Mellitus
Barchetta I, Dule S, Cimini F, Sentinelli F, Oldani A, Passarella G, et al.
Diabetes Metab Res Rev . 2024 Dec; 41(1):e70018. PMID: 39655684
Context: The mechanisms underlying bone fragility and increased fracture risk observed in individuals with type 2 diabetes (T2D) are not yet fully elucidated. Previous research has suggested a role for...
3.
Waist circumference, among metabolic syndrome components, predicts degraded trabecular bone score: a retrospective study of a female population from the 2005-2008 NHANES cohorts
Totaro M, Barchetta I, Sentinelli F, Cimini F, Palazzi S, DAlessandro F, et al.
Front Endocrinol (Lausanne) . 2024 Dec; 15:1476751. PMID: 39640886
Background: Osteoporosis and metabolic syndrome (MetS) are conditions associated with ageing and chronic inflammation; among MetS' components, visceral obesity has been correlated to low bone mineral density in postmenopausal women....
4.
Renal Expression and Localization of the Receptor for (Pro)renin and Its Ligands in Rodent Models of Diabetes, Metabolic Syndrome, and Age-Dependent Focal and Segmental Glomerulosclerosis
Iacobini C, Vitale M, Sentinelli F, Haxhi J, Pugliese G, Menini S
Int J Mol Sci . 2024 Feb; 25(4). PMID: 38396894
The (pro)renin receptor ((P)RR), a versatile protein found in various organs, including the kidney, is implicated in cardiometabolic conditions like diabetes, hypertension, and dyslipidemia, potentially contributing to organ damage. Importantly,...
5.
Reduced Lipopolysaccharide-Binding Protein (LBP) Levels Are Associated with Non-Alcoholic Fatty Liver Disease (NAFLD) and Adipose Inflammation in Human Obesity
Barchetta I, Cimini F, Sentinelli F, Chiappetta C, Di Cristofano C, Silecchia G, et al.
Int J Mol Sci . 2023 Dec; 24(24). PMID: 38139003
Lipopolysaccharide (LPS) and its binding protein LBP have emerged as potential contributors to the progression from overweight/obesity to overt metabolic diseases and NAFLD. While LPS is known to activate hepatocyte...
6.
Neurotensin Gene rs2234762 C>G Variant Associates with Reduced Circulating Pro-NT Levels and Predicts Lower Insulin Resistance in Overweight/Obese Children
Sentinelli F, Barchetta I, Cimini F, Dule S, Bailetti D, Cossu E, et al.
Int J Mol Sci . 2023 Apr; 24(7). PMID: 37047432
Neurotensin (NT) is a small protein implicated in the regulation of energy balance which acts as both a neurotransmitter in the central nervous system and as a gastrointestinal peptide. In...
7.
Deep Resequencing of 9 Candidate Genes Identifies a Role for ARAP1 and IGF2BP2 in Modulating Insulin Secretion Adjusted for Insulin Resistance in Obese Southern Europeans
Bailetti D, Sentinelli F, Prudente S, Cimini F, Barchetta I, Totaro M, et al.
Int J Mol Sci . 2022 Feb; 23(3). PMID: 35163144
Type 2 diabetes is characterized by impairment in insulin secretion, with an established genetic contribution. We aimed to evaluate common and low-frequency (1-5%) variants in nine genes strongly associated with...
8.
Circulating pro-neurotensin levels predict bodyweight gain and metabolic alterations in children
Barchetta I, Bertoccini L, Sentinelli F, Bailetti D, Marini G, Cimini F, et al.
Nutr Metab Cardiovasc Dis . 2021 Feb; 31(3):902-910. PMID: 33549442
Background And Aims: Neurotensin (NT) is an intestinal peptide released after fat ingestion, which regulates appetite and facilitates lipid absorption. Elevated plasma levels of its stable precursor pro-neurotensin (pro-NT) are...
9.
Granzyme B Expression in Visceral Adipose Tissue Associates With Local Inflammation and Glyco-Metabolic Alterations in Obesity
Cimini F, Barchetta I, Ceccarelli V, Chiappetta C, Di Biasio A, Bertoccini L, et al.
Front Immunol . 2020 Dec; 11:589188. PMID: 33312176
Granzyme B (GrB) is a serine protease produced by immune and non-immune cells, able to promote multiple processes, like apoptosis, inflammation, extracellular matrix remodeling and fibrosis. GrB expression in visceral...
10.
Circulating dipeptidyl peptidase-4 is independently associated with the presence and severity of NAFLD/NASH in individuals with and without obesity and metabolic disease
Barchetta I, Ceccarelli V, Cimini F, Barone E, Sentinelli F, Coluzzi M, et al.
J Endocrinol Invest . 2020 Aug; 44(5):979-988. PMID: 32852705
Introduction: Dipeptidyl peptidase 4 (DPP4) levels are associated to metabolic and cardiovascular diseases in humans; initial evidence reported a relationship between DPP4 and chronic liver diseases. Aim of this study...