Federica Gibellini
Overview
Explore the profile of Federica Gibellini including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
2155
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Recent Articles
11.
Herishanu Y, Perez-Galan P, Liu D, Biancotto A, Pittaluga S, Vire B, et al.
Blood
. 2010 Oct;
117(2):563-74.
PMID: 20940416
Chronic lymphocytic leukemia (CLL), an incurable malignancy of mature B lymphocytes, involves blood, bone marrow, and secondary lymphoid organs such as the lymph nodes (LN). A role of the tissue...
12.
Richmond G, Gibellini F, Young S, Major L, Denton H, Lilley A, et al.
Parasitology
. 2010 Jul;
137(9):1357-92.
PMID: 20602846
The biological membranes of Trypanosoma brucei contain a complex array of phospholipids that are synthesized de novo from precursors obtained either directly from the host, or as catabolised endocytosed lipids....
13.
Gibellini F, Smith T
IUBMB Life
. 2010 May;
62(6):414-28.
PMID: 20503434
The glycerophospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE) account for greater than 50% of the total phospholipid species in eukaryotic membranes and thus play major roles in the structure and function...
14.
Aue G, Njuguna N, Tian X, Soto S, Hughes T, Vire B, et al.
Haematologica
. 2009 Sep;
94(9):1266-73.
PMID: 19734418
Background: In chronic lymphocytic leukemia lenalidomide causes striking immune activation, possibly leading to clearance of tumor cells. We conducted this study to investigate the mechanism of action of lenalidomide and...
15.
Gibellini F, Hunter W, Smith T
Mol Microbiol
. 2009 Jun;
73(5):826-43.
PMID: 19555461
Phosphatidylethanolamine (GPEtn), a major phospholipid component of trypanosome membranes, is synthesized de novo from ethanolamine through the Kennedy pathway. Here the composition of the GPEtn molecular species in the bloodstream...
16.
Sarcon A, Desierto M, Zhou W, Visconte V, Gibellini F, Chen J, et al.
Exp Hematol
. 2009 Feb;
37(4):477-86.
PMID: 19216020
Objective: To investigate the role of perforin-mediated cell apoptosis in murine models of immune-mediated bone marrow (BM) failure. Materials And Methods: We compared C57BL/6J (B6) mice carrying a perforin gene...
17.
Gibellini F, Hunter W, Smith T
Biochem J
. 2008 May;
415(1):135-44.
PMID: 18489261
Ethanolamine and choline are major components of the trypanosome membrane phospholipids, in the form of GPEtn (phosphatidylethanolamine) [corrected] and GPCho (phosphatidylcholine) [corrected] . Ethanolamine is also found as an integral...
18.
Rizzatti E, Mora-Jensen H, Weniger M, Gibellini F, Lee E, Daibata M, et al.
Leuk Lymphoma
. 2008 Apr;
49(4):798-808.
PMID: 18398749
Bortezomib is more active against mantle cell lymphoma (MCL) than against most other lymphoma subtypes. Nevertheless, up to half of patients with MCL have bortezomib resistant disease. Factors contributing to...
19.
Cavazzuti A, Paglietti G, Hunter W, Gamarro F, Piras S, Loriga M, et al.
Proc Natl Acad Sci U S A
. 2008 Feb;
105(5):1448-53.
PMID: 18245389
Pteridine reductase (PTR1) is essential for salvage of pterins by parasitic trypanosomatids and is a target for the development of improved therapies. To identify inhibitors of Leishmania major and Trypanosoma...
20.
Solomou E, Wong S, Visconte V, Gibellini F, Young N
Br J Haematol
. 2007 Jun;
138(1):72-6.
PMID: 17555449
In aplastic anaemia, T cells have a central role in the pathophysiology of bone marrow destruction. This study showed that T cells from patients with aplastic anaemia expressed decreased T-cell...