Federica Brugnoli
Overview
Explore the profile of Federica Brugnoli including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
407
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Recent Articles
1.
Gallo M, Ferrari E, Brugnoli F, Terrazzan A, Ancona P, Volinia S, et al.
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940737
Breast Cancer (BrCa) exhibits a high phenotypic heterogeneity, leading to the emergence of aggressive clones and the development of drug resistance. Considering the BrCa heterogeneity and that metabolic reprogramming is...
2.
Pierantoni M, Grassilli S, Brugnoli F, DellAira M, Bertagnolo V
Life Sci
. 2024 Jun;
350:122762.
PMID: 38843994
Type 1 diabetes (T1D) is a chronic autoimmune condition characterized by the destruction of pancreatic β cells, recently estimated to affect approximately 8.75 million individuals worldwide. At variance with conventional...
3.
Brugnoli F, DellAira M, Tedeschi P, Grassilli S, Pierantoni M, Foschi R, et al.
Cells
. 2024 May;
13(10.
PMID: 38786044
Breast cancer includes tumor subgroups with morphological, molecular, and clinical differences. Intrinsic heterogeneity especially characterizes breast tumors with a triple negative phenotype, often leading to the failure of even the...
4.
Gates E, Calvert N, Cundy N, Brugnoli F, Navals P, Kirby A, et al.
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628729
Transglutaminase 2 (TG2) is a multifunctional enzyme primarily responsible for crosslinking proteins. Ubiquitously expressed in humans, TG2 can act either as a transamidase by crosslinking two substrates through formation of...
5.
Gallo M, Ferrari E, Terrazzan A, Brugnoli F, Spisni A, Taccioli C, et al.
FEBS J
. 2023 Aug;
290(22):5411-5433.
PMID: 37597264
Transglutaminase 2 (TG2), which mediates post-translational modifications of multiple intracellular enzymes, is involved in the pathogenesis and progression of cancer. We used H-NMR metabolomics to study the effects of AA9,...
6.
Tedeschi P, Brugnoli F, Merighi S, Grassilli S, Nigro M, Catani M, et al.
Antioxidants (Basel)
. 2023 Feb;
12(2).
PMID: 36830057
Voghiera garlic is an Italian white garlic variety which obtained in 2010 the Protected Designation of Origin. It is widely used for culinary purposes or as an ingredient for supplement...
7.
Canella R, Brugnoli F, Gallo M, Keillor J, Terrazzan A, Ferrari E, et al.
Cancers (Basel)
. 2023 Jan;
15(1).
PMID: 36612174
Since the multifunctionality of transglutaminase 2 (TG2) includes extra- and intracellular functions, we investigated the effects of intracellular administration of TG2 inhibitors in three breast cancer cell lines, MDA-MB-231, MDA-MB-436...
8.
Grassilli S, Bertagnolo V, Brugnoli F
Diagnostics (Basel)
. 2022 Sep;
12(9).
PMID: 36140539
The miR-29 family comprises miR-29a, miR-29b, and miR-29c, and these molecules play crucial and partially overlapped functions in solid tumors, in which the different isoforms are variously de-regulated and mainly...
9.
Grassilli S, Brugnoli F, Cairo S, Bianchi N, Judde J, Bertagnolo V
J Pers Med
. 2022 Jun;
12(6).
PMID: 35743776
Triple negative breast cancer (TNBC) represents the most aggressive breast tumor, showing a high intrinsic variability in terms of both histopathological features and response to therapies. Blocking the Akt signaling...
10.
Corra F, Crudele F, Baldassari F, Bianchi N, Galasso M, Minotti L, et al.
Genes (Basel)
. 2021 Dec;
12(12).
PMID: 34946928
In the human genome, there are about 600 ultra-conserved regions (UCRs), long DNA sequences extremely conserved in vertebrates. We performed a large-scale study to quantify transcribed UCR (T-UCR) and miRNA...