Fazle Hussain
Overview
Explore the profile of Fazle Hussain including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
452
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Recent Articles
1.
Khan Z, Hussain F
Cell Physiol Biochem
. 2024 Jun;
58(3):250-272.
PMID: 38865588
Background/aims: Motivated by the vacuolar proton pump's importance in cancer, we investigate the effects of proton pump inhibition on breast cancer cell migration and proliferation, F-actin polymerization, lamin A/C, heterochromatin,...
2.
Roy M, Hussain F
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791386
Metastasis in breast cancer is the major cause of death in females (about 30%). Based on our earlier observation that Vitamin D3 downregulates mTOR, we hypothesized that Vitamin D3 conjugated...
3.
Munir M, Ahsan Halim S, Santos J, Khan F, Khan A, Rahman M, et al.
Cell Physiol Biochem
. 2023 Apr;
57(2):105-122.
PMID: 37052042
Background/aims: Macrophages interact with tumor cells within the tumor microenvironment (TME), which plays a crucial role in tumor progression. Cancer cells also can instruct macrophages to facilitate the spread of...
4.
Khan Z, Van Bussel F, Hussain F
PLoS One
. 2022 Aug;
17(8):e0268332.
PMID: 35976910
Motivated by several possible differences in Covid-19 virus strains, age demographics, and face mask wearing between continents and countries, we focussed on changes in Covid death rates in 2020. We...
5.
Sufian H, Santos J, Khan Z, Ahsan Halim S, Khan A, Munir M, et al.
Life Sci
. 2022 May;
301:120610.
PMID: 35525305
Aims: Breast cancer metastasis is the leading cause of mortality among breast cancer patients. Epithelial to mesenchymal transition (EMT) is a biological process that plays a fundamental role in facilitating...
6.
Munir M, Kay M, Kang M, Rahman M, Al-Harrasi A, Choudhury M, et al.
Int J Mol Sci
. 2021 Jul;
22(12).
PMID: 34207035
Breast cancer is the most commonly occurring cancer in women of Western countries and is the leading cause of cancer-related mortality. The breast tumor microenvironment contains immune cells, fibroblasts, adipocytes,...
7.
Khan Z, Hussain F
Cell Mol Bioeng
. 2020 Dec;
13(6):591-604.
PMID: 33281989
Introduction: Cells in the tumor microenvironment experience mechanical stresses, such as compression generated by uncontrolled cell growth within a tissue, increased substrate stiffness due to tumor cell extracellular matrix (ECM)...
8.
Munir M, Ponce C, Santos J, Sufian H, Al-Harrasi A, Gollahon L, et al.
Mol Biol Rep
. 2020 Sep;
47(10):7771-7782.
PMID: 32990902
Obesity is associated with hypercholesterolemia and is a global epidemic. Epidemiological and animal studies revealed cholesterol is an essential regulator of estrogen receptor positive (ER+) breast cancer progression while inhibition...
9.
Santos J, Hussain F
Nutr Cancer
. 2019 Aug;
72(5):734-746.
PMID: 31437005
Cancer cells overexpress several transcription factors and motor proteins, such as NFkB and kinesin, to accommodate their high energy demand as well as migratory needs via enhanced glycolysis. We hypothesize...
10.
Khan Z, Santos J, Vaz N, Hussain F
Biomicrofluidics
. 2019 Aug;
13(3):034110.
PMID: 31431812
Highly metastatic prostate cancer cells flowing through a microfluidic channel form plasma membrane blebs: they form 27% more than normal cells and have a lower stiffness (about 50%). Hypo-osmotic stress...