Faten El Hage
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Explore the profile of Faten El Hage including associated specialties, affiliations and a list of published articles.
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10
Citations
227
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Recent Articles
1.
El Hage F, Durgeau A, Mami-Chouaib F
Ann N Y Acad Sci
. 2013 Jan;
1283:75-80.
PMID: 23302073
We identified that the antigen preprocalcitonin (ppCT) is recognized on a human lung carcinoma by a cytotoxic T lymphocyte clone derived from autologous tumor-infiltrating lymphocytes. The antigenic peptide ppCT(16-25) is...
2.
Durgeau A, El Hage F, Vergnon I, Validire P, de Montpreville V, Besse B, et al.
J Immunol
. 2011 Oct;
187(11):5532-9.
PMID: 22025554
Decreased antigenicity of cancer cells is a major problem in tumor immunology. This is often acquired by an expression defect in the TAP. However, it has been reported that certain...
3.
Noman M, Buart S, van Pelt J, Richon C, Hasmim M, Leleu N, et al.
J Immunol
. 2009 Mar;
182(6):3510-21.
PMID: 19265129
Hypoxia is an essential component of tumor microenvironment. In this study, we investigated the influence of hypoxia (1% PO(2)) on CTL-mediated tumor cell lysis. We demonstrate that exposure of target...
4.
El Hage F, Stroobant V, Vergnon I, Baurain J, Echchakir H, Lazar V, et al.
Proc Natl Acad Sci U S A
. 2008 Jul;
105(29):10119-24.
PMID: 18626012
We identified an antigen recognized on a human non-small-cell lung carcinoma by a cytotoxic T lymphocyte clone derived from autologous tumor-infiltrating lymphocytes. The antigenic peptide is presented by HLA-A2 and...
5.
El Hage F, Abouzahr-Rifai S, Meslin F, Mami-Chouaib F, Chouaib S
Bull Cancer
. 2008 Jan;
95(1):57-67.
PMID: 18230571
Cellular transformation is initiated by genetic and epigenetic mutations that activate oncogenes and inactivate tumor suppressor pathways. Cancers thus arise when somatic cells escape intrinsic and extrinsic tumor suppressor mechanisms...
6.
Friedlein G, El Hage F, Vergnon I, Richon C, Saulnier P, Lecluse Y, et al.
J Immunol
. 2007 May;
178(11):6821-7.
PMID: 17513730
We previously characterized several tumor-specific T cell clones from PBL and tumor-infiltrating lymphocytes of a lung cancer patient with identical TCR rearrangements and similar lytic potential, but with different antitumor...
7.
Chouaib S, El Hage F, Benlalam H, Mami-Chouaib F
Med Sci (Paris)
. 2006 Sep;
22(8-9):755-9.
PMID: 16962052
The notion that the immune system regulates cancer development is now well established. An overwhelming amount of data from animal models, together with compelling data from human patients, indicate that...
8.
El Hage F, Vergnon I, Grunenwald D, Soria J, Chouaib S, Mami-Chouaib F
Oncol Rep
. 2005 Aug;
14(3):763-9.
PMID: 16077989
We have identified an antigen recognized on a large cell carcinoma of the lung by tumor-specific cytotoxic T lymphocytes (CTL). The antigenic peptide is encoded by a mutated alpha-actinin-4 gene...
9.
Dorothee G, Vergnon I, El Hage F, Le Maux Chansac B, Ferrand V, Lecluse Y, et al.
J Immunol
. 2005 May;
174(11):6888-97.
PMID: 15905531
We have isolated from tumor-infiltrating lymphocytes (TIL) and PBL of a lung carcinoma patient several tumor-specific T cell clones displaying similar peptide-MHC tetramer staining and expressing a unique TCR. Although...
10.
Dorothee G, Echchakir H, Le Maux Chansac B, Vergnon I, El Hage F, Moretta A, et al.
Oncogene
. 2003 Oct;
22(46):7192-8.
PMID: 14562047
T lymphocytes infiltrating a human lung carcinoma stimulated in vitro with autologous tumor cell line showed a TCRVbeta13.6(+) T-cell expansion. This subset was isolated using TCRVbeta-specific antibody and several T-cell...