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Fariz F Alkassis

Explore the profile of Fariz F Alkassis including associated specialties, affiliations and a list of published articles. Areas
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Citations 13
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Recent Articles
1.
Doll C, Pereira N, Hashimi M, Grindrod T, Alkassis F, Cai L, et al.
Sci Rep . 2021 Mar; 11(1):6608. PMID: 33758249
Cardiac development is a dynamic process, temporally and spatially. When disturbed, it leads to congenital cardiac anomalies that affect approximately 1% of live births. Genetic variants in several loci lead...
2.
Cai L, Alkassis F, Kasahara H
Dev Dyn . 2020 Jan; 249(5):636-645. PMID: 31900966
Background: Vasculature is formed by responding to homeostatic tissue demands including in developing hearts. Hypoxia generally stimulates vascular formation in which vascular endothelial growth factor A (VEGF-A) plays a critical...
3.
Cai L, Tanada Y, D Bello G, Fleming J, Alkassis F, Ladd T, et al.
Sci Rep . 2019 Aug; 9(1):12580. PMID: 31467300
Cardiac contractility is enhanced by phosphorylation of myosin light chain 2 (MLC2) by cardiac-specific MLC kinase (cMLCK), located at the neck region of myosin heavy chain. In normal mouse and...
4.
Tougas C, Grindrod T, Cai L, Alkassis F, Kasahara H
Front Physiol . 2019 Jun; 10:696. PMID: 31244672
Recent studies identified heterozygous variants in gene that encodes cardiac myosin light chain kinase (cMLCK) are related to familial dilated cardiomyopathy (DCM) for the first time. Autosomal dominant traits suggest...