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Fangshu Ye

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Articles 11
Citations 13
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Recent Articles
1.
Ye F, Wang C, OConnor A
PLoS One . 2023 Dec; 18(12):e0296020. PMID: 38128003
Randomized clinical trials (RCTs) are designed for measuring the effectiveness of the treatments and testing a hypothesis regarding the relative effect between two or more treatments. Trial designers are often...
2.
Rawal G, Almeida M, Gauger P, Zimmerman J, Ye F, Rademacher C, et al.
Viruses . 2023 Nov; 15(11). PMID: 38005910
The recently emerged PRRSV 1-4-4 L1C variant (L1C.5) was in vivo and in vitro characterized in this study in comparison with three other contemporary 1-4-4 isolates (L1C.1, L1A, and L1H)...
3.
Hakimi M, Ye F, Stinman C, Sahin O, Burrough E
J Vet Diagn Invest . 2023 Nov; 36(1):62-69. PMID: 37968893
Swine dysentery, caused by and the newly recognized in grower-finisher pigs, is a substantial economic burden in many swine-rearing countries. Antimicrobial therapy is the only commercially available measure to control...
4.
Ye F, Wang C, OConnor A
BMC Med Res Methodol . 2023 Nov; 23(1):267. PMID: 37951877
Background: Planning the design of a new trial comparing two treatments already in a network of trials with an a-priori plan to estimate the effect size using a network meta-analysis...
5.
Armenta-Leyva B, Munguia-Ramirez B, Cheng T, Ye F, Henao-Diaz A, Gimenez-Lirola L, et al.
J Vet Diagn Invest . 2023 Nov; 36(1):78-85. PMID: 37919959
Normalization, the process of controlling for normal variation in sampling and testing, can be achieved in real-time PCR assays by converting sample quantification cycles (Cqs) to "efficiency standardized Cqs" (ECqs)....
6.
Munguia-Ramirez B, Armenta-Leyva B, Henao-Diaz A, Ye F, Baum D, Gimenez-Lirola L, et al.
Vet Sci . 2023 Jun; 10(6). PMID: 37368767
Endogenous reference genes are used in gene-expression studies to "normalize" the results and, increasingly, as internal sample controls (ISC) in diagnostic quantitative polymerase chain reaction (qPCR). Three studies were conducted...
7.
Armenta-Leyva B, Munguia-Ramirez B, Gimenez-Lirola L, Lin X, Ye F, Zimmerman J
J Vet Diagn Invest . 2023 Jun; 35(5):521-527. PMID: 37337714
Based on publications reporting improvements in real-time PCR (rtPCR) performance, we compared protocols based on heat treatment or dilution followed by direct rtPCR to standard extraction and amplification methods for...
8.
Ye F, Wang C, OConnor A
Front Pharmacol . 2023 May; 14:1157708. PMID: 37188261
To achieve higher power or increased precision for a new trial, methods based on updating network meta-analysis (NMA) have been proposed by researchers. However, this approach could potentially lead to...
9.
Munguia-Ramirez B, Armenta-Leyva B, Henao-Diaz A, Cheng T, Zhang J, Rawal G, et al.
J Vet Diagn Invest . 2023 May; 35(4):374-383. PMID: 37166086
We characterized the effect of 1) temperature × time, 2) freeze-thaw cycles, and 3) high porcine reproductive and respiratory syndrome virus (PRRSV) RNA concentrations on the detection of PRRSV and...
10.
Hu D, Wang C, Ye F, OConnor A
BMC Med Res Methodol . 2022 Nov; 22(1):299. PMID: 36418960
Background: A critical step in trial design is determining the sample size and sample allocation to ensure the proposed study has sufficient power to test the hypothesis of interest: superiority,...