Fangchen Gong
Overview
Explore the profile of Fangchen Gong including associated specialties, affiliations and a list of published articles.
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15
Citations
185
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0
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Recent Articles
1.
Xie R, Tan D, Liu B, Xiao G, Gong F, Zhang Q, et al.
MedComm (2020)
. 2025 Jan;
6(2):e70074.
PMID: 39866839
Acute respiratory distress syndrome (ARDS) is a clinical syndrome of acute hypoxic respiratory failure caused by diffuse lung inflammation and edema. ARDS can be precipitated by intrapulmonary factors or extrapulmonary...
2.
Gong F, Zheng X, Xu W, Xie R, Liu W, Pei L, et al.
MedComm (2020)
. 2025 Jan;
6(2):e70049.
PMID: 39822760
Pulmonary endothelial cell (EC) activation is a key factor in acute respiratory distress syndrome (ARDS). In sepsis, increased glycolysis leads to lactate buildup, which induces lysine lactylation (Kla) on histones...
3.
Gong F, Zheng X, Zhao S, Liu H, Chen E, Xie R, et al.
MedComm (2020)
. 2025 Jan;
6(2):e70058.
PMID: 39822757
Disseminated intravascular coagulation (DIC) is a complex and serious condition characterized by widespread activation of the coagulation cascade, resulting in both thrombosis and bleeding. This review aims to provide a...
4.
Liu W, Wang X, Xu D, Gong F, Pei L, Yang S, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Dec;
1871(3):167613.
PMID: 39643219
Acute pancreatitis (AP) is a severe inflammatory disorder associated with metabolic reprogramming and mitochondrial dysfunction. This study investigated central carbon metabolism alterations in pancreatic acinar cells during AP, elucidated the...
5.
Gong F, Liu W, Pei L, Wang X, Zheng X, Yang S, et al.
Front Endocrinol (Lausanne)
. 2024 Aug;
15:1377755.
PMID: 39205680
Sepsis, a life-threatening condition, involves complex interactions among metabolic alterations, inflammatory mediators, and host responses. This study utilized a bidirectional Mendelian randomization approach to investigate the causal relationships between 1400...
6.
Zheng X, Wang Y, Wang Y, Wang X, Pei L, Zhao S, et al.
Front Immunol
. 2024 Jul;
15:1417716.
PMID: 39076981
Background: Sepsis is a life-threatening organ dysfunction resulting from a dysregulated host response to infection, yet the potential causal relationship between the immunophenotype and sepsis remains unclear. Methods: Genetic variants...
7.
Liu W, Wang X, Zhao S, Yang S, Zheng X, Gong F, et al.
Front Immunol
. 2024 Apr;
15:1374787.
PMID: 38601150
Background: Acute pancreatitis (AP) is a severe digestive system disorder with a significant risk of progressing to sepsis, a major cause of mortality. Unraveling the immunological pathways in AP is...
8.
Pei L, Li R, Wang X, Xu D, Gong F, Chen W, et al.
Int Immunopharmacol
. 2024 Jan;
128:111575.
PMID: 38280334
Sepsis-associated liver dysfunction (SALD) aggravates the disease progression and prognosis of patients. Macrophages in the liver play a crucial role in the occurrence and development of SALD. Human umbilical cord...
9.
Huang S, Chen Y, Gong F, Chen W, Zheng Y, Zhao B, et al.
Heliyon
. 2024 Jan;
10(1):e23266.
PMID: 38187232
Background: In addition to excessive inflammation, immunosuppression has been recognized as a contributing factor to poor prognosis of sepsis. Although it has been reported that T cells can become functionally...
10.
Liu W, Gong F, Zheng X, Pei L, Wang X, Yang S, et al.
J Med Virol
. 2023 Dec;
95(12):e29342.
PMID: 38130170
Shanghai has faced an unprecedented COVID-19 pandemic with the BA.2.2 strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron infection. Comprehensive insights into its epidemiology, clinical manifestations, and viral...