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Fan Niu

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Articles 24
Citations 222
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Recent Articles
11.
Li Y, Zhang L, Zhang Y, Miao Z, Liu Z, Zhou G, et al.
Phytomedicine . 2022 Sep; 107:154445. PMID: 36130463
Background: Guiqi Baizhu Decoction (GQBZD) has a good protective effect on radiation-induced intestinal edema (RIIE). However, the underlying molecular mechanisms need further elucidation. Purpose: To reveal the potential mechanism of...
12.
Feng H, Liu Y, Zhang M, Liu R, Wang J, Wang W, et al.
Biochem Biophys Res Commun . 2022 Sep; 629:152-158. PMID: 36122452
Acute myeloid leukemia (AML) is the most common blood cancer in adults. Patients' 5-year overall survival is less than 30% thus having a poor prognosis. To date, the development of...
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Ma B, Feng H, Feng C, Liu Y, Zhang H, Wang J, et al.
Adv Sci (Weinh) . 2022 Mar; 9(13):e2104850. PMID: 35239999
The Bcr/Abl plays a central role in Philadelphia chromosome-positive (Ph+) leukemia because of the constitutively activated Abl tyrosine kinase and its downstream pathways. Currently, the clinical treatment of imatinib-resistant patients...
15.
Li Y, Zhang Y, Wei K, He J, Ding N, Hua J, et al.
Front Cell Infect Microbiol . 2021 Jul; 11:577236. PMID: 34307184
Gut microbiota is regarded as the second human genome and forgotten organ, which is symbiotic with the human host and cannot live and exist alone. The gut microbiota performs multiple...
16.
Zhang C, Zou Y, Zhu Y, Liu Y, Feng H, Niu F, et al.
Front Med (Lausanne) . 2021 Apr; 8:649326. PMID: 33869254
Pancreatic cancer is a highly lethal malignancy globally. This study aimed to probe and validate immune-related prognostic mRNAs as therapeutic targets for pancreatic cancer. Gene transcriptome data of pancreatic cancer...
17.
He W, Yan J, Jiang W, Li S, Qu Y, Niu F, et al.
Chem Mater . 2020 Sep; 30(20):7034-7046. PMID: 32982042
Peptide-tuned self-assembly of macromolecular agents (>500 Da) such as therapeutic peptides offers a strategy to improve the properties and biofunctions of degradable nanomaterials, but the tough requirement of macromolecular therapeutics...
18.
He X, Wang J, You X, Niu F, Fan L, Lv Y
Spectrochim Acta A Mol Biomol Spectrosc . 2020 Jul; 241:118665. PMID: 32683249
Drug crime is a prominent issue of concern from pole to pole. In order to seek higher profits, drug gangs often add diluents and adulterants to the drugs to disperse...
19.
Ma B, Niu F, Qu X, He W, Feng C, Wang S, et al.
Biomaterials . 2019 Mar; 204:1-12. PMID: 30861422
A major pharmacological barrier to peptide therapeutics is their susceptibility to proteolytic degradation and poor membrane permeability, which, in principle, can be overcome by nanoparticle-based delivery technologies. Proteins, by definition,...
20.
Li X, Tolbert W, Hu H, Gohain N, Zou Y, Niu F, et al.
Chem Sci . 2019 Feb; 10(5):1522-1530. PMID: 30809370
Two major pharmacological hurdles severely limit the widespread use of small peptides as therapeutics: poor proteolytic stability and membrane permeability. Importantly, low aqueous solubility also impedes the development of peptides...