Fallon K Noto
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Explore the profile of Fallon K Noto including associated specialties, affiliations and a list of published articles.
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10
Citations
1016
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0
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Recent Articles
1.
OConnor C, Taylor S, Miller K, Hurst L, Haanen T, Suhan T, et al.
Cancer Res
. 2021 Dec;
82(4):721-733.
PMID: 34921012
Significance: A drug repurposing screen identifies synthetic lethal interactions in PP2A-deficient uterine serous carcinoma, providing potential therapeutic avenues for treating this deadly endometrial cancer.
2.
Noto F, Sangodkar J, Adedeji B, Moody S, McClain C, Tong M, et al.
PLoS One
. 2020 Oct;
15(10):e0240169.
PMID: 33027304
We have created the immunodeficient SRG rat, a Sprague-Dawley Rag2/Il2rg double knockout that lacks mature B cells, T cells, and circulating NK cells. This model has been tested and validated...
3.
Noto F, Adjan-Steffey V, Tong M, Ravichandran K, Zhang W, Arey A, et al.
Mol Cancer Ther
. 2018 Sep;
17(11):2481-2489.
PMID: 30206106
The rat is the preferred model for toxicology studies, and it offers distinctive advantages over the mouse as a preclinical research model including larger sample size collection, lower rates of...
4.
Cayo M, Mallanna S, Di Furio F, Jing R, Tolliver L, Bures M, et al.
Cell Stem Cell
. 2017 Apr;
20(4):478-489.e5.
PMID: 28388428
Efforts to identify pharmaceuticals to treat heritable metabolic liver diseases have been hampered by the lack of models. However, cells with hepatocyte characteristics can be produced from induced pluripotent stem...
5.
Noto F, Determan M, Cai J, Cayo M, Mallanna S, Duncan S
BMC Res Notes
. 2014 Jul;
7:437.
PMID: 25002137
Background: The characterization of induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) routinely includes analyses of chromosomal integrity. The belief is that pluripotent stem cells best suited to...
6.
Cayo M, Cai J, DeLaForest A, Noto F, Nagaoka M, Clark B, et al.
Hepatology
. 2012 Jun;
56(6):2163-71.
PMID: 22653811
Unlabelled: Elevated levels of low-density lipoprotein cholesterol (LDL-C) in plasma are a major contributor to cardiovascular disease, which is the leading cause of death worldwide. Genome-wide association studies (GWAS) have...
7.
Gundry R, Riordon D, Tarasova Y, Chuppa S, Bhattacharya S, Juhasz O, et al.
Mol Cell Proteomics
. 2012 Apr;
11(8):303-16.
PMID: 22493178
Induction of a pluripotent state in somatic cells through nuclear reprogramming has ushered in a new era of regenerative medicine. Heterogeneity and varied differentiation potentials among induced pluripotent stem cell...
8.
DeLaForest A, Nagaoka M, Si-Tayeb K, Noto F, Konopka G, Battle M, et al.
Development
. 2011 Aug;
138(19):4143-53.
PMID: 21852396
The availability of pluripotent stem cells offers the possibility of using such cells to model hepatic disease and development. With this in mind, we previously established a protocol that facilitates...
9.
Si-Tayeb K, Noto F, Sepac A, Sedlic F, Bosnjak Z, Lough J, et al.
BMC Dev Biol
. 2010 Aug;
10:81.
PMID: 20682060
Background: The use of lentiviruses to reprogram human somatic cells into induced pluripotent stem (iPS) cells could limit their therapeutic usefulness due to the integration of viral DNA sequences into...
10.
Si-Tayeb K, Noto F, Nagaoka M, Li J, Battle M, Duris C, et al.
Hepatology
. 2009 Dec;
51(1):297-305.
PMID: 19998274
Unlabelled: There exists a worldwide shortage of donor livers available for orthotropic liver transplantation and hepatocyte transplantation therapies. In addition to their therapeutic potential, primary human hepatocytes facilitate the study...