Fahimeh Raoufi
Overview
Explore the profile of Fahimeh Raoufi including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
124
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Recent Articles
1.
Chernyak N, Bhagwat B, Naravula S, Chen Y, Solban N, Zhang F, et al.
J Med Chem
. 2024 Sep;
67(18):16222-16234.
PMID: 39235949
Toll-like receptor (TLR) activation converts immunologically inactive tumors into immunologically active tumors by activating tumor residing antigen-presenting cells and recruitment of cytotoxic T lymphocytes. Targeted immune agonists (TIAs) are antibody...
2.
Hollingsworth S, Noland C, Vroom K, Saha A, Sam M, Gao Q, et al.
Sci Rep
. 2023 Aug;
13(1):13668.
PMID: 37608223
Coronaviruses have been the causative agent of three epidemics and pandemics in the past two decades, including the ongoing COVID-19 pandemic. A broadly-neutralizing coronavirus therapeutic is desirable not only to...
3.
Pande K, Hollingsworth S, Sam M, Gao Q, Singh S, Saha A, et al.
Front Immunol
. 2022 May;
13:864775.
PMID: 35603164
The SARS-CoV-2 pandemic and particularly the emerging variants have deepened the need for widely available therapeutic options. We have demonstrated that hexamer-enhancing mutations in the Fc region of anti-SARS-CoV IgG...
4.
Zhang S, Chen M, Zhou S, Raoufi F, Wiswell D, Hsieh S, et al.
J Immunol Methods
. 2021 Mar;
494:113047.
PMID: 33775673
Peggy Sue is a capillary-based western/immunoassay platform that can separate and characterize proteins by size or charge. A quick and automated immunogenicity assay was developed on Peggy Sue based on...
5.
Ma F, Raoufi F, Bailly M, Fayadat-Dilman L, Tomazela D
MAbs
. 2020 May;
12(1):1763762.
PMID: 32370592
Characterization of charge heterogeneity in monoclonal antibodies (mAbs) is needed during developability assessment and downstream development of drug candidates. Charge heterogeneity can come from post-translational modifications like deamidation, isomerization, and...
6.
Bailly M, Mieczkowski C, Juan V, Metwally E, Tomazela D, Baker J, et al.
MAbs
. 2020 Apr;
12(1):1743053.
PMID: 32249670
Monoclonal antibodies play an increasingly important role for the development of new drugs across multiple therapy areas. The term 'developability' encompasses the feasibility of molecules to successfully progress from discovery...
7.
Falk B, Liang Y, Bailly M, Raoufi F, Kekec A, Pissarnitski D, et al.
Chembiochem
. 2019 Jul;
21(3):315-319.
PMID: 31283075
NMR measurements of rotational and translational diffusion are used to characterize the solution behavior of a wide variety of therapeutic proteins and peptides. The timescales of motions sampled in these...
8.
Chao C, Joyce-Shaikh B, Grein J, Moshrefi M, Raoufi F, LaFace D, et al.
PLoS One
. 2011 Jul;
6(7):e22256.
PMID: 21799806
C17 was first described about ten years ago as a gene expressed in CD34+ cells. A more recent study has suggested a role for C17 in chondrogenesis and development of...