Fadi Saade
Overview
Explore the profile of Fadi Saade including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
390
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0
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Recent Articles
1.
Capitani M, Saade F, Havas K, Angeletti M, Concetti F, Agas D, et al.
Curr Gene Ther
. 2014 May;
14(3):161-9.
PMID: 24828254
Background: DNA vaccines provide high tolerability and safety but commonly suffer from suboptimal immunogenicity. We previously reported that a plasmid vector (pATRex), encoding the DNA sequence for the von Willebrand...
2.
Saade F, Honda-Okubo Y, Trec S, Petrovsky N
Vaccine
. 2013 Jan;
31(15):1999-2007.
PMID: 23306367
Although current HBV vaccines have an outstanding record of safety and efficacy, reduced immunogenicity is a problem in those of older age, or having renal impairment or diabetes mellitus. In...
3.
Saade F, Gorski S, Petrovsky N
Expert Rev Vaccines
. 2012 Dec;
11(12):1459-70.
PMID: 23252389
There is a need for novel approaches to tackle major vaccine challenges such as malaria, tuberculosis and HIV, among others. Success will require vaccines able to induce a cytotoxic T-cell...
4.
Li L, Saade F, Petrovsky N
J Biotechnol
. 2012 Sep;
162(2-3):171-82.
PMID: 22981627
DNA vaccines have evolved greatly over the last 20 years since their invention, but have yet to become a competitive alternative to conventional protein or carbohydrate based human vaccines. Whilst...
5.
Honda-Okubo Y, Saade F, Petrovsky N
Vaccine
. 2012 Jun;
30(36):5373-81.
PMID: 22728225
Advax™ adjuvant is derived from inulin, a natural plant-derived polysaccharide that when crystallized in the delta polymorphic form, becomes immunologically active. This study was performed to assess the ability of...
6.
Saade F, Petrovsky N
Expert Rev Vaccines
. 2012 Feb;
11(2):189-209.
PMID: 22309668
Despite many years of research, human DNA vaccines have yet to fulfill their early promise. Over the past 15 years, multiple generations of DNA vaccines have been developed and tested...
7.
Saade F, Buronfosse T, Pradat P, Abdul F, Cova L
Vaccine
. 2008 Jun;
26(40):5159-64.
PMID: 18554756
We explored in the duck hepatitis B virus (DHBV) model the impact of duck interferon gamma (Du-IFNgamma) or interleukin 2 (Du-IL2) co-delivery on humoral neutralizing response induced by DNA-based vaccine...
8.
Narayan R, Buronfosse T, Schultz U, Chevallier-Gueyron P, Guerret S, Chevallier M, et al.
J Gen Virol
. 2006 Oct;
87(Pt 11):3225-3232.
PMID: 17030856
Gamma interferon (IFN-gamma) expression plays a crucial role in the control of mammalian hepatitis B virus (HBV) infection. However, the role of duck INF-gamma (DuIFN-gamma) in the outcome of duck...
9.
Martin G, Ferrier B, Conjard A, Martin M, Nazaret R, Boghossian M, et al.
Biochem J
. 2006 Sep;
401(2):465-73.
PMID: 17002601
Recent reports have indicated that 48-72 h of fasting, Type 1 diabetes and high-protein feeding induce gluconeogenesis in the small intestine of adult rats in vivo. Since this would (i)...