Fabrice Lestienne
Overview
Explore the profile of Fabrice Lestienne including associated specialties, affiliations and a list of published articles.
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10
Citations
91
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Recent Articles
1.
Thouvenin M, Bacquey A, Babin M, Lestienne F, Lauze C, Gravier E, et al.
Dermatol Ther (Heidelb)
. 2023 Oct;
13(12):3137-3151.
PMID: 37837493
Introduction: Pruritus is a prevalent symptom, described as one of the most bothersome of psoriasis. Specific itch management remains a challenge, for which hydrotherapy could be used as adjunct care...
2.
Mars M, Neant I, Leclerc C, Bosch S, Rouviere C, Moreau M, et al.
J Allergy Clin Immunol
. 2021 Oct;
149(4):1348-1357.
PMID: 34653514
Background: Type-17 inflammation characterizes psoriasis, a chronic skin disease. Because several inflammatory cytokines contribute to psoriasis pathogenesis, inhibiting the simultaneous production of these cytokines in T17 cells may be beneficial...
3.
Newman-Tancredi A, Martel J, Cosi C, Heusler P, Lestienne F, Varney M, et al.
J Pharm Pharmacol
. 2017 Jun;
69(9):1178-1190.
PMID: 28612503
Objectives: NLX-112 (befiradol, F13640) is a selective serotonin 5-HT receptor agonist. Although it has been tested in vivo, little has been reported on its in vitro signal transduction profile. Methods:...
4.
Lauressergues E, Heusler P, Lestienne F, Troulier D, Rauly-Lestienne I, Tourette A, et al.
Pharmacol Res Perspect
. 2016 Apr;
4(2):e00214.
PMID: 27069629
The Hedgehog (HH) pathway has been linked to the formation of basal cell carcinoma (BCC), medulloblastoma, and other cancers. The recently approved orally active drugs vismodegib (GDC-0449) and sonidegib (LDE-225)...
5.
Vispe S, Deroide A, Davoine E, Desjobert C, Lestienne F, Fournier L, et al.
Oncotarget
. 2015 May;
6(17):15265-82.
PMID: 25948775
5-azacytidine and 5-aza-2'-deoxycytidine are clinically used to treat patients with blood neoplasia. Their antileukemic property is mediated by the trapping and the subsequent degradation of a family of proteins, the...
6.
Rauly-Lestienne I, Lestienne F, Ailhaud M, Binesse J, Newman-Tancredi A, Cussac D
Cell Signal
. 2010 Aug;
23(1):58-64.
PMID: 20727408
Following agonist action, G-protein-coupled receptors may exhibit differential coupling to G-proteins or second messenger pathways, supporting the notion of agonist-directed trafficking. To explore these mechanisms, we have designed and transfected...
7.
Bruins Slot L, Lestienne F, Grevoz-Barret C, Newman-Tancredi A, Cussac D
Eur J Pharmacol
. 2009 Aug;
620(1-3):27-35.
PMID: 19695244
Brain region-specific modulation of immediate-early gene (IEG) may constitute a marker of antipsychotic drug-like activity. We investigated the effects of the putative antipsychotic drug N-[(2,2-dimethyl-2,3-dihydro-benzofuran-7-yloxy)ethyl]-3-(cyclopent-1-enyl)-benzylamine (F15063), a compound that targets...
8.
Rival Y, Puech L, Taillandier T, Beneteau N, Rouquette A, Lestienne F, et al.
Eur J Pharmacol
. 2009 Apr;
606(1-3):121-9.
PMID: 19374865
Atherosclerotic complications are related to the unstable character of the plaque rather than its volume. Vulnerable plaques often contain a large lipid core, a reduced content of smooth muscle cells...
9.
Rival Y, Stennevin A, Puech L, Rouquette A, Cathala C, Lestienne F, et al.
J Pharmacol Exp Ther
. 2004 Jul;
311(2):467-75.
PMID: 15273253
Peroxisome proliferator-activated receptors (PPARs) regulate storage and catabolism of fats and carbohydrates. PPARgamma activity increases insulin sensitivity and adipocyte differentiation at the expense of adipogenesis and weight gain. The goal...
10.
Rival Y, Beneteau N, Chapuis V, Taillandier T, Lestienne F, Dupont-Passelaigue E, et al.
DNA Cell Biol
. 2004 Jun;
23(5):283-92.
PMID: 15169608
It is now recognized that atherosclerosis complications are related to the unstable character of the plaque rather than its volume. Vulnerable plaques often contain a large lipid core, a reduced...