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Fabrice Lesage

Explore the profile of Fabrice Lesage including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 418
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Recent Articles
11.
Pontoizeau C, Roda C, Arnoux J, Vignolo-Diard P, Brassier A, Habarou F, et al.
Mol Genet Metab . 2020 Apr; 130(2):110-117. PMID: 32273051
Purpose: We aimed to identify prognostic factors for survival and long-term intellectual and developmental outcome in neonatal patients with early-onset urea cycle disorders (UCD) experiencing hyperammonaemic coma. Methods: We retrospectively...
12.
Tuchmann-Durand C, Thevenet E, Moulin F, Lesage F, Bouchereau J, Oualha M, et al.
JIMD Rep . 2020 Feb; 51(1):25-29. PMID: 32071836
Beta-hydroxybutyrate (BHB) is a synthetic ketone body used as an adjuvant energy substrate in the treatment of patients with metabolic cardiomyopathy. A medication prescribing error led to the administration of...
13.
Rapp M, Urien S, Foissac F, Beranger A, Bouazza N, Benaboud S, et al.
Eur J Clin Pharmacol . 2019 Oct; 76(1):61-71. PMID: 31654149
Purpose: We aimed to develop a meropenem population pharmacokinetic (PK) model in critically ill children and simulate dosing regimens in order to optimize patient exposure. Methods: Meropenem plasma concentration was...
14.
Levy M, Moshous D, Szezepanski I, Galmiche L, Castelle M, Lesage F, et al.
Eur Respir J . 2019 Oct; 54(5). PMID: 31649064
Introduction: Pulmonary hypertension is a rare but important cause of mortality after haematopoietic stem cell transplantation (HSCT) in children. This complication is poorly characterised in the literature. We report here...
15.
Beranger A, Benaboud S, Urien S, Moulin F, Bille E, Lesage F, et al.
Clin Pharmacokinet . 2018 Jun; 58(2):223-233. PMID: 29862466
Background: Critically ill children frequently display observed alterations of pharmacokinetic (PK) parameters, leading to a reduction in β-lactam concentrations. This study aimed to develop a PK population model for piperacillin...
16.
Oualha M, Chardot C, Debray D, Lesage F, Harroche A, Renolleau S, et al.
Br J Clin Pharmacol . 2018 Feb; 84(6):1206-1214. PMID: 29423936
Aims: Preventing post-liver transplantation (LT) hepatic artery and portal vein thrombosis includes enoxaparin administration. Enoxaparin pharmacokinetics (PK) has not been investigated in children following LT. We described an enoxaparin PK...
17.
Genuini M, Oualha M, Bouazza N, Moulin F, Treluyer J, Lesage F, et al.
Pediatr Crit Care Med . 2018 Feb; 19(6):e263-e269. PMID: 29394210
Objective: Describe and assess a continuous infusion dosing scheme of vancomycin therapy in critically ill children. Design: Retrospective single-center study, January to June 2015. Setting: PICU located within a French...
18.
Heilbronner C, Merckx A, Brousse V, Allali S, Hubert P, De Montalembert M, et al.
Pediatr Crit Care Med . 2018 Jan; 19(5):e235-e241. PMID: 29356722
Objectives: To describe the need for transfusion and short- and long-term evolutions of pediatric sickle cell disease patients with acute chest syndrome for whom early continuous noninvasive ventilation represented first-line...
19.
Abi-Warde M, Roda C, Arnoux J, Servais A, Habarou F, Brassier A, et al.
J Inherit Metab Dis . 2017 Sep; 40(6):783-792. PMID: 28905140
Background: Maple syrup urine disease (MSUD) is a rare disease that requires a protein-restricted diet for successful management. Little is known, however, about the psychosocial outcome of MSUD patients. This...
20.
Tabone L, Mediamolle N, Bellesme C, Lesage F, Grevent D, Ozanne A, et al.
Stroke . 2017 May; 48(8):2278-2281. PMID: 28546326
Background And Purpose: To evaluate hyperacute management of pediatric arterial ischemic stroke, setting up dedicated management pathways is the first recommended step to prove the feasibility and safety of such...