Fabio Rogerio de Moraes
Overview
Explore the profile of Fabio Rogerio de Moraes including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
131
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Recent Articles
1.
Kaihara J, de Moraes F, Nunes P, Alves M, Cavalli R, Tasic L, et al.
PLoS One
. 2024 Nov;
19(11):e0314053.
PMID: 39591465
Preeclampsia, a pregnancy-specific syndrome, poses substantial risks to maternal and neonatal health, particularly in cases with severe features. Our study focuses on evaluating the impact of low molecular weight metabolites...
2.
Omage F, Salim J, Mazoni I, Yano I, Borro L, Gonzalez J, et al.
Comput Struct Biotechnol J
. 2024 Nov;
23:3907-3919.
PMID: 39559776
Allosteric regulation plays a crucial role in modulating protein functions and represents a promising strategy in drug development, offering enhanced specificity and reduced toxicity compared to traditional active site inhibition....
3.
Justa H, Gonzalez J, Vuitika L, Mariutti R, Magnago P, de Moraes F, et al.
Int J Mol Sci
. 2023 Aug;
24(15).
PMID: 37569382
Spiders of genus are widely distributed and their venoms contain phospholipases D (PLDs), which degrade phospholipids and trigger inflammatory responses, dermonecrosis, hematological changes, and renal injuries. Biochemical, functional, and structural...
4.
Chaves-Moreira D, Gremski L, de Moraes F, Vuitika L, Wille A, Gonzalez J, et al.
Toxins (Basel)
. 2023 Feb;
15(2).
PMID: 36828423
Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade...
5.
Gismene C, Gonzalez J, Santisteban A, Nascimento A, Dos Santos Cunha L, de Moraes F, et al.
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077258
Staphylococcal exfoliative toxins (ETs) are glutamyl endopeptidases that specifically cleave the Glu381-Gly382 bond in the ectodomains of desmoglein 1 (Dsg1) via complex action mechanisms. To date, four ETs have been...
6.
Mazoni I, Salim J, de Moraes F, Borro L, Neshich G
PLoS One
. 2020 Dec;
15(12):e0244315.
PMID: 33378364
Secondary structure elements are generally found in almost all protein structures revealed so far. In general, there are more β-sheets than α helices found inside the protein structures. For example,...
7.
Lopes T, de Moraes F, Tedesco A, Arni R, Rahal P, Calmon M
Biomed Pharmacother
. 2020 Dec;
136:111175.
PMID: 33358325
No abstract available.
8.
Lopes T, de Moraes F, Tedesco A, Arni R, Rahal P, Calmon M
Biomed Pharmacother
. 2020 Feb;
125:110038.
PMID: 32098685
No abstract available.
9.
Lopes T, de Moraes F, Tedesco A, Arni R, Rahal P, Calmon M
Biomed Pharmacother
. 2019 Dec;
123:109794.
PMID: 31874443
Renal cell carcinoma (RCC) consists of the most lethal common urological cancer and the clinical practice has shown that resistant RCC to commons therapies is extremely high. Berberine is an...
10.
Minari K, de Azevedo E, Rodrigues Kiraly V, Batista F, de Moraes F, de Melo F, et al.
Int J Biol Macromol
. 2019 Feb;
130:125-138.
PMID: 30797004
Hsp90s are key proteins in cellular homeostasis since they interact with many client proteins. Several studies indicated that Hsp90s are potential targets for treating diseases, such as cancer or malaria....