Fabio Pittella Silva
Overview
Explore the profile of Fabio Pittella Silva including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
802
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0
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Recent Articles
1.
Morais K, Arcanjo D, Lopes G, da Silva G, da Mota T, Gabriel T, et al.
Cell Biochem Funct
. 2019 Apr;
37(4):273-280.
PMID: 31012504
Telomerase is a good target for new anticancer drug development because it is present in over 85% of human tumours. However, despite chronic therapy is a condition for anti-telomerase approach,...
2.
Colaco C, de Matos A, Estrela M, Rocha-Junior M, Otaguiri K, Rodrigues E, et al.
Arch Virol
. 2017 Jun;
162(10):3131-3136.
PMID: 28608127
Approximately 5% of human T-cell leukemia virus type 1 (HTLV-1)-infected individuals will develop one of the HTLV-1-related diseases, such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) or adult T-cell leukemia. However,...
3.
de Oliveira D, Ferreira Lima R, Clarencio J, Velozo E, de Amorim I, da Mota T, et al.
Neurochem Int
. 2016 Jun;
99:33-41.
PMID: 27292695
Currently, there is no effective therapy for high grade gliomas. 8-Methoxypsoralen (8-MOP) is a compound used in the treatment of skin diseases combined with UV light irradiation. In this work,...
4.
Oliveira-Santos W, Rabello D, Lucena-Araujo A, de Oliveira F, Rego E, Silva F, et al.
Tumour Biol
. 2016 Jan;
37(7):9473-81.
PMID: 26790435
SET and MYND domain containing 2 (SMYD2) and the SET and MYND domain containing 3 (SMYD3) are the most studied and well-characterized members of SMYD family. It has been demonstrated...
5.
Figueiredo D, do Amaral Rabello D, Zanette D, Saggioro F, Mamede R, Zago M, et al.
Oncol Rep
. 2015 Jan;
33(4):2017-22.
PMID: 25633166
Larynx cancer is the second most common type of cancer among all head and neck cancers. Deregulation of epigenetic effectors, including altered expression of histone methyltransferases from the MLL (mixed...
6.
do Amaral Rabello D, Lucena-Araujo A, Alves-Silva J, da Eira V, de Vasconcellos M, de Oliveira F, et al.
Blood Cells Mol Dis
. 2014 Aug;
54(1):97-102.
PMID: 25131810
EZH2, a histone methyltransferase, is overexpressed in several human tumors, but whether it exerts any impact in chronic lymphocytic leukemia (CLL) remains unknown. We used real time PCR to investigate...
7.
Laforest A, Aparicio T, Zaanan A, Silva F, Didelot A, Desbeaux A, et al.
Eur J Cancer
. 2014 May;
50(10):1740-1746.
PMID: 24797764
Aim Of The Study: Small bowel adenocarcinoma (SBA) is a rare and aggressive tumour with poor outcomes. Because of its low incidence, the number prospective studies remains insufficient leading to...
8.
Faria J, Correa N, de Andrade C, de Angelis Campos A, Dos Santos Samuel de Almeida R, Rodrigues T, et al.
J Cancer Sci Ther
. 2014 Apr;
5(2):58-65.
PMID: 24738023
Cancer is comprised of a multitude of epigenetic abnormalities, including the global loss and regional gain of DNA methylation as well as alterations in histone methylation. Here, we characterize a...
9.
Toshihiro Sakamoto L, de Andrade R, Felipe M, Motoyama A, Silva F
Leuk Res
. 2014 Mar;
38(4):496-502.
PMID: 24631370
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Although several clinical characteristics can be associated with worse prognosis, more robust biological markers still remains uncovered. SMYD2, a member...
10.
do Amaral Rabello D, de Moura C, de Andrade R, Motoyama A, Silva F
Int J Oncol
. 2013 Jun;
43(2):653-60.
PMID: 23754336
The histone lysine methyltransferases contain a SET domain, which catalyzes the addition of methyl groups to specific lysine residues. The MLL family of genes encodes histone-modifying enzymes with histone 3-lysine...