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Fabio H Silva

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Articles 19
Citations 179
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Recent Articles
1.
Calmasini F, Alexandre E, Oliveira M, Silva F, Soares A, Costa S, et al.
J Physiol Biochem . 2021 May; 77(4):557-564. PMID: 34018097
Lipopolysaccharide (LPS) is a component of gram-negative bacteria wall that elicits inflammatory response in the host through the toll-like receptor 4 (TLR4) activation. In the lower urinary tract (LUT), bacteria-derived...
2.
Musicki B, Karakus S, La Favor J, Chen H, Silva F, Sturny M, et al.
J Cell Physiol . 2020 Sep; 236(4):3073-3082. PMID: 32974910
Priapism, a prolonged penile erection in the absence of sexual arousal, is common among patients with sickle cell disease (SCD). Hypogonadism is also common in patients with SCD. While the...
3.
Musicki B, Anele U, Campbell J, Karakus S, Shiva S, Silva F, et al.
Life Sci . 2019 Oct; 238:116922. PMID: 31634463
Aims: Nitric oxide (NO) has a critical, but not well understood, influence in the physiology of the lower urinary tract. We evaluated the effect of NO/phosphodiesterase (PDE)5 signaling in voiding...
4.
Karakus S, Anele U, Silva F, Musicki B, Burnett A
Am J Physiol Renal Physiol . 2019 Jun; 317(3):F540-F546. PMID: 31215803
Voiding abnormalities are common among the sickle cell disease (SCD) population, among which overactive bladder (OAB) syndrome is observed at rates as high as 39%. Although detrusor overactivity is the...
5.
Alexandre E, Calmasini F, Sponton A, de Oliveira M, Andre D, Silva F, et al.
Eur J Pharmacol . 2018 Aug; 836:25-33. PMID: 30102890
Obese mice display overactive bladder (OAB) associated with impaired urethra smooth muscle (USM) function. In this study, we evaluated the role of the adipose tissue surrounding the urethra and prostate...
6.
Lanaro C, Franco-Penteado C, Silva F, Fertrin K, Dos Santos J, Wade M, et al.
Exp Hematol . 2017 Nov; 58:35-38. PMID: 29108926
Fetal hemoglobin (HbF) induction by hydroxyurea (HU) therapy is associated with decreased morbidity and mortality in sickle cell anemia (SCA) patients, but not all patients respond to or tolerate HU....
7.
Alexandre E, de Oliveira M, Campos R, Kiguti L, Calmasini F, Silva F, et al.
Am J Physiol Renal Physiol . 2017 Mar; 312(6):F1026-F1034. PMID: 28298357
Urethral smooth muscle (USM) contributes to urinary continence by contracting during the urine storage phase, which is mainly mediated by activation of postjunctional α-adrenoceptors. Males and females show differences in...
8.
Sponton A, Silva F, Araujo H, Valgas da Silva C, Moraes C, Antunes E, et al.
J Vasc Res . 2017 Mar; 54(1):33-50. PMID: 28288470
Background: The aim of the present study was to evaluate different signaling pathways by which exercise training would interfere in endothelial function in obesity. Therefore, we examined adipocytokine levels and...
9.
Silva F, Claudino M, Calmasini F, Alexandre E, Franco-Penteado C, Burnett A, et al.
PLoS One . 2016 Dec; 11(12):e0166291. PMID: 27935981
Background: Sickle cell disease patients display priapism that may progress to erectile dysfunction. However, little is known about the pathophysiological alterations of corpus cavernosum in sickle cell disease. Objective: Thus,...
10.
Silva F, Karakus S, Musicki B, Matsui H, Bivalacqua T, Dos Santos J, et al.
J Pharmacol Exp Ther . 2016 Aug; 359(2):230-237. PMID: 27540002
Patients with sickle cell disease (SCD) display priapism, and dysregulated nitric oxide (NO) pathway may contribute to this condition. However, current therapies offered for the prevention of priapism in SCD...