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Fabio Bessa Lima

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Articles 38
Citations 401
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Recent Articles
1.
Bolin A, de Fatima Silva F, Salgueiro R, Dos Santos B, Komino A, Andreotti S, et al.
J Cell Physiol . 2024 Aug; 239(9):1-12. PMID: 39091018
Chronic and excessive glucocorticoid (GC) exposure can cause Cushing's syndrome, resulting in fat accumulation in selected body areas. Particularly in the brown adipose tissue (BAT), GC acts negatively, resulting in...
2.
Salgueiro R, Bolin A, Andreotti S, Komino A, de Sousa E, de Fatima Silva F, et al.
Mol Cell Endocrinol . 2024 Apr; 589:112250. PMID: 38663485
The most common form of hypercortisolism is iatrogenic Cushing's syndrome. Lipodystrophy and metabolic disorders can result from the use of exogenous glucocorticoids (GC). Adipocytes play an important role in the...
3.
Andreotti S, Komino A, de Fatima Silva F, Ramos A, Gil N, Azevedo G, et al.
Front Endocrinol (Lausanne) . 2023 Nov; 14:1259854. PMID: 38027196
Background: Intrauterine food restriction (IFR) during pregnancy is associated with low birth weight (LBW) and obesity in adulthood. It is known that white adipose tissue (WAT) plays critical metabolic and...
4.
de Souza C, Stopa L, Martins A, Wunderlich A, Lopes G, de Fatima Silva F, et al.
Front Physiol . 2023 May; 14:1161582. PMID: 37234421
Lactation overnutrition is a programming agent of energy metabolism, and litter size reduction leads to the early development of obesity, which persists until adulthood. Liver metabolism is disrupted by obesity,...
5.
de Fatima Silva F, Komino A, Andreotti S, Boltes Reis G, Caminhotto R, Landgraf R, et al.
Biomedicines . 2022 Sep; 10(9). PMID: 36140428
Chronic hypercortisolism has been associated with the development of several metabolic alterations, mostly caused by the effects of chronic glucocorticoid (GC) exposure over gene expression. The metabolic changes can be...
6.
Sena-Junior A, Aidar F, de Oliveira E Silva A, Dos Santos Estevam C, Carvalho C, Lima F, et al.
Nutrients . 2021 Jan; 13(1). PMID: 33396291
Diabetes mellitus is one of the most prevalent chronic diseases in the world; one of its main characteristics is chronic hyperglycemia. Pharmacotherapy and other alternatives such as regular exercise are...
7.
Figueira da Costa T, Andreotti S, de Farias T, Lima F, Bargi-Souza P
J Biol Rhythms . 2020 Sep; 35(6):530-541. PMID: 32886018
In adipose tissue, the expression of hundreds of genes exhibits circadian oscillation, which may or may not be affected by circulating melatonin levels. Using control and pinealectomized rats, we investigated...
8.
Junior A, Aidar F, Dos Santos J, Dos Santos Estevam C, Dos Santos J, de Oliveira E Silva A, et al.
BMC Sports Sci Med Rehabil . 2020 Aug; 12:45. PMID: 32774865
Background: Type 1 (T1DM) is a metabolic disease characterized by hyperglycemia and excessive generation of reactive oxygen species caused by autoimmune destruction of beta-cells in the pancreas. Among the antioxidant...
9.
Rosa Santos L, DE Araujo S, Vieira E, Dos Santos Estevam C, Dos Santos J, Wichi R, et al.
Medicina (Kaunas) . 2020 May; 56(5). PMID: 32384612
The practice of physical exercise, especially resistance exercise, is important for the treatment and/or prevention of cardiovascular risk factors in adult individuals. However, there are few studies on its effects...
10.
de Oliveira Caminhotto R, Andreotti S, Komino A, de Fatima Silva F, Laurato Sertie R, Christoffolete M, et al.
Life Sci . 2019 Jul; 232:116683. PMID: 31344430
Aims: Previous work has demonstrated that ketogenic diets promote white fat browning; however, the exact mechanisms underlying this phenomenom have yet to be elucidated. Recently, an in vitro study showed...