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Fabien Pernot

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Articles 8
Citations 128
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Recent Articles
1.
Stamboulian-Platel S, Legendre A, Chabrol T, Platel J, Pernot F, Duveau V, et al.
Exp Neurol . 2016 Jul; 284(Pt A):11-28. PMID: 27443630
Mesiotemporal lobe Epilepsy (MTLE), the most frequent form of focal epilepsy, is often drug-resistant. Enriching the epileptic focus with GABA-releasing engineered cells has been proposed as a strategy to prevent...
2.
Greget R, Dadak S, Barbier L, Lauga F, Linossier-Pierre S, Pernot F, et al.
Neurotoxicology . 2016 Apr; 54:140-152. PMID: 27108687
Exposure to organophosphorus (OP) compounds, either pesticides or chemical warfare agents, represents a major health problem. As potent irreversible inhibitors of cholinesterase, OP may induce seizures, as in status epilepticus,...
3.
Bouteiller J, Legendre A, Allam S, Ambert N, Hu E, Greget R, et al.
Annu Int Conf IEEE Eng Med Biol Soc . 2013 Feb; 2012:6612-5. PMID: 23367445
One of the fundamental characteristics of the brain is its hierarchical and temporal organization: scales in both space and time must be considered to fully grasp the system's underlying mechanisms...
4.
Bouteiller J, Allam S, Hu E, Greget R, Ambert N, Keller A, et al.
Annu Int Conf IEEE Eng Med Biol Soc . 2012 Jan; 2011:445-8. PMID: 22254344
The brain is a perfect example of an integrated multi-scale system, as the complex interactions taking place at the molecular level regulate neuronal activity that further modifies the function of...
5.
Dhote F, Carpentier P, Barbier L, Peinnequin A, Baille V, Pernot F, et al.
Toxicol Appl Pharmacol . 2012 Jan; 259(2):195-209. PMID: 22245128
Epileptic seizures and status epilepticus (SE) induced by the poisoning with organophosphorus nerve agents (OP), like soman, are accompanied by neuroinflammation whose role in seizure-related brain damage (SRBD) is not...
6.
Greget R, Pernot F, Bouteiller J, Ghaderi V, Allam S, Keller A, et al.
PLoS One . 2011 Dec; 6(12):e28380. PMID: 22194830
Activation of several subtypes of glutamate receptors contributes to changes in postsynaptic calcium concentration at hippocampal synapses, resulting in various types of changes in synaptic strength. Thus, while activation of...
7.
Pernot F, Heinrich C, Barbier L, Peinnequin A, Carpentier P, Dhote F, et al.
Epilepsia . 2011 Sep; 52(12):2315-25. PMID: 21955106
Purpose: Neuroinflammation appears as a prominent feature of the mesiotemporal lobe epilepsy syndrome (MTLE) that is observed in human patients and animal models. However, the precise temporal relationship of its...
8.
Pernot F, Dorandeu F, Beaup C, Peinnequin A
J Neurosci Res . 2009 Nov; 88(5):1000-8. PMID: 19937810
Reference genes are often used to normalize expression of data from real-time quantitative reverse transcription-polymerase chain reaction (RT-qPCR), and only a validation of their stability during a given experimental paradigm...