F P T Baaijens
Overview
Explore the profile of F P T Baaijens including associated specialties, affiliations and a list of published articles.
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54
Citations
1033
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Recent Articles
1.
Ristori T, Bouten C, Baaijens F, Loerakker S
Acta Biomater
. 2018 Sep;
80:203-216.
PMID: 30223090
The hemodynamic functionality of heart valves strongly depends on the distribution of collagen fibers, which are their main load-bearing constituents. It is known that collagen networks remodel in response to...
2.
Ristori T, Notermans T, Foolen J, Kurniawan N, Bouten C, Baaijens F, et al.
Sci Rep
. 2018 Jun;
8(1):8518.
PMID: 29867153
Adherent cells are generally able to reorient in response to cyclic strain. In three-dimensional tissues, however, extracellular collagen can affect this cellular response. In this study, a computational model able...
3.
Ghazanfari S, Driessen-Mol A, Bouten C, Baaijens F
Acta Biomater
. 2016 Mar;
35:118-26.
PMID: 26923531
Statement Of Significance: Collagen fiber orientation is a significant determinant of the mechanical properties of native tissues. To mimic the native-like collagen alignment in vitro, we need to understand the...
4.
Ristori T, Obbink-Huizer C, Oomens C, Baaijens F, Loerakker S
Comput Methods Biomech Biomed Engin
. 2016 Jan;
19(12):1347-58.
PMID: 26823159
Understanding collagen and stress fiber remodeling is essential for the development of engineered tissues with good functionality. These processes are complex, highly interrelated, and occur over different time scales. As...
5.
Oomen P, Loerakker S, van Geemen D, Neggers J, Goumans M, van den Bogaerdt A, et al.
Acta Biomater
. 2015 Nov;
29:161-169.
PMID: 26537200
Statement Of Significance: Annually, over 280,000 heart valve replacements are performed worldwide. Tissue engineering has the potential to provide valvular disease patients with living valve substitutes that can last a...
6.
Vigliotti A, Ronan W, Baaijens F, Deshpande V
Biomech Model Mechanobiol
. 2015 Sep;
15(4):761-89.
PMID: 26338672
We present a model for stress-fiber reorganization and the associated contractility that includes both the kinetics of stress-fiber formation and dissociation as well as the kinetics of stress-fiber remodeling. These...
7.
Brugmans M, Sntjens S, Cox M, Nandakumar A, Bosman A, Mes T, et al.
Acta Biomater
. 2015 Aug;
27:21-31.
PMID: 26316031
The emerging field of in situ tissue engineering (TE) of load bearing tissues places high demands on the implanted scaffolds, as these scaffolds should provide mechanical stability immediately upon implantation....
8.
Argento G, de Jonge N, Sontjens S, Oomens C, Bouten C, Baaijens F
Biomech Model Mechanobiol
. 2014 Oct;
14(3):603-13.
PMID: 25319256
The anisotropic collagen architecture of an engineered cardiovascular tissue has a major impact on its in vivo mechanical performance. This evolving collagen architecture is determined by initial scaffold microstructure and...
9.
Romgens A, Bader D, Bouwstra J, Baaijens F, Oomens C
J Mech Behav Biomed Mater
. 2014 Oct;
40:397-405.
PMID: 25305633
Microneedles represent promising tools for delivery of drugs to the skin. However, before these microneedles can be used in clinical practice, it is essential to understand the process of skin...
10.
The influence of matrix (an)isotropy on cardiomyocyte contraction in engineered cardiac microtissues
van Spreeuwel A, Bax N, Bastiaens A, Foolen J, Loerakker S, Borochin M, et al.
Integr Biol (Camb)
. 2014 Feb;
6(4):422-9.
PMID: 24549279
In the cardiac microenvironment, cardiomyocytes (CMs) are embedded in an aligned and structured extracellular matrix (ECM) to maintain the coordinated contractile function of the heart. The cardiac fibroblast (cFB) is...