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F J Woerner

Explore the profile of F J Woerner including associated specialties, affiliations and a list of published articles. Areas
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Citations 23
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1.
Jadhav P, Woerner F, Lam P, Hodge C, Eyermann C, Man H, et al.
J Med Chem . 1998 May; 41(9):1446-55. PMID: 9554878
Comparison of the high-resolution X-ray structures of the native HIV-1 protease and its complexes with the inhibitors suggested that the enzyme flaps are flexible. The movement at the tip of...
2.
Jadhav P, Ala P, Woerner F, Chang C, Garber S, Anton E, et al.
J Med Chem . 1997 Jan; 40(2):181-91. PMID: 9003516
Cyclic urea amides, a novel series of HIV-1 protease (HIV PR) inhibitors, have increased activity against drug-resistant mutants of the HIV PR. The design strategy for these inhibitors is based...