F J Accurso
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Explore the profile of F J Accurso including associated specialties, affiliations and a list of published articles.
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53
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1093
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Recent Articles
1.
Jain R, Beckett V, Konstan M, Accurso F, Burns J, Mayer-Hamblett N, et al.
J Cyst Fibros
. 2018 Jan;
17(4):484-491.
PMID: 29292092
Background: Chronic Pseudomonas aeruginosa (Pa) airways infection, exuberant local inflammation, and progressive lung function loss are hallmarks of cystic fibrosis (CF). KB001-A is an anti-PcrV PEGylated monoclonal antibody fragment to...
2.
Taylor-Cousar J, Janssen J, Wilson A, Clair C, Pickard K, Jones M, et al.
J Diabetes Res
. 2016 Dec;
2016:1527932.
PMID: 27999822
. Cystic fibrosis related diabetes (CFRD) is the most common comorbidity in patients with CF. In spite of increased screening, diagnosis, and treatment of CFRD, the mortality rate in patients...
3.
Taylor-Cousar J, Wiley C, Felton L, St Clair C, Jones M, Curran-Everett D, et al.
J Cyst Fibros
. 2014 Dec;
14(2):228-36.
PMID: 25466700
Rationale: Airway inflammation is central to cystic fibrosis (CF) pathophysiology. Pre-clinical models have shown that phosphodiesterase inhibitors (PDEi) like sildenafil have anti-inflammatory activity. PDEi have not been studied in CF...
4.
Cooley J, Sontag M, Accurso F, Remold-ODonnell E
Eur Respir J
. 2010 Sep;
37(5):1083-90.
PMID: 20817705
Neutrophil serine proteases (NSPs), especially elastase, are major agents of lung destruction in cystic fibrosis (CF) patients. This study investigated SerpinB1, a highly efficient inhibitor of NSPs, in CF lung...
5.
Rubio F, Cooley J, Accurso F, Remold-ODonnell E
Thorax
. 2004 Mar;
59(4):318-23.
PMID: 15047952
Background: In patients with cystic fibrosis (CF) neutrophils are recruited in excess to the airways yet pathogens are not cleared and the patients suffer from chronic infections. Recent studies have...
6.
Davies P, ERSKINE J, Hambidge K, Accurso F
Eur J Clin Nutr
. 2002 Oct;
56(10):940-6.
PMID: 12373612
Objective: To determine when energy expenditure becomes elevated in infants with cystic fibrosis (CF). Design: Longitudinal studies of total energy expenditure (TEE) using doubly labeled water were conducted in infants...
7.
Sagel S, Kapsner R, Osberg I, Sontag M, Accurso F
Am J Respir Crit Care Med
. 2001 Nov;
164(8 Pt 1):1425-31.
PMID: 11704590
A noninvasive method to characterize inflammation and infection in the airways of nonexpectorating children with cystic fibrosis (CF) is needed for clinical and research purposes. Accordingly, we performed sputum inductions...
8.
Oermann C, Sockrider M, Giles D, Sontag M, Accurso F, Castile R
Pediatr Pulmonol
. 2001 Oct;
32(5):372-7.
PMID: 11596162
Enhanced airway clearance is thought to result in better-maintained pulmonary function in cystic fibrosis (CF). Postural drainage, percussion, and vibration (PDPV) have been the primary airway clearance technique (ACT) employed...
9.
Wojtczak H, Kerby G, Wagener J, Copenhaver S, Gotlin R, Riches D, et al.
Pediatr Pulmonol
. 2001 Sep;
32(4):293-302.
PMID: 11568990
Inhaled corticosteroids are commonly used in cystic fibrosis (CF), but there are few studies evaluating their safety in young children. We, therefore, prospectively administered beclomethasone diproprionate (BDP) to 12 clinically...
10.
Krebs N, Westcott J, Arnold T, Kluger B, Accurso F, MILLER L, et al.
Pediatr Res
. 2000 Aug;
48(2):256-61.
PMID: 10926304
Low plasma zinc concentrations have been reported in approximately 30% of young infants with cystic fibrosis identified by newborn screening. The objective of this study was to examine zinc homeostasis...