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F G Spinale

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Articles 188
Citations 2214
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Recent Articles
1.
Coker M, Spinale F
Cardiovasc Pathol . 2015 Apr; 7(3):161-8. PMID: 25851223
The myocardial fibrillar collagens ensure structural integrity of adjoining myocytes, provide the means by which myocyte shortening is translated into overall left ventricular (LV) pump function, and have been postulated...
2.
Warters R, Szabo T, Spinale F, DeSantis S, Reves J
Anaesthesia . 2011 Jan; 66(3):163-7. PMID: 21265818
We wished to test the hypothesis that neuromuscular blockade facilitates mask ventilation. In order reliably and reproducibly to assess the efficiency of mask ventilation, we developed a novel grading scale...
3.
Gunasinghe S, Ikonomidis J, Spinale F
Curr Drug Targets Cardiovasc Haematol Disord . 2003 May; 1(2):75-91. PMID: 12769658
Changes in cardiovascular tissue structure can result in alterations in function. This process occurs as a continuum and can be defined as cardiovascular remodeling. A family of zinc dependent proteases...
4.
Multani M, Krombach R, Goldberg A, King M, HENDRICK J, SAMPLE J, et al.
J Cardiovasc Pharmacol Ther . 2002 Mar; 6(4):369-76. PMID: 11907639
Background: The present study examined the effects of acute angiotensin-converting enzyme inhibition (ACEI), AT(1) receptor blockade (AT(1) block), or combined treatment on in vitro and in vivo bradykinin (BK) levels....
5.
Wilson E, Spinale F
Ann Med . 2002 Jan; 33(9):623-34. PMID: 11817657
The progression of left ventricular (LV) dysfunction is often accompanied by changes in LV geometry and myocardial architecture that can be defined as LV myocardial remodelling. An important event in...
6.
Multani M, Krombach R, HENDRICK J, Baicu S, Joffs C, SAMPLE J, et al.
J Card Fail . 2002 Jan; 7(4):348-54. PMID: 11782859
Background: We examined whether and to what degree long-term angiotensin-converting enzyme (ACE) inhibition, angiotensin type 1 (AT(1))-receptor blockade, or combined inhibition in developing congestive heart failure (CHF) alter myocardial interstitial...
7.
Lucas Jr D, Patterson T, HENDRICK J, Holder J, SAMPLE J, Joffs C, et al.
J Cardiovasc Pharmacol . 2001 Oct; 38(4):618-24. PMID: 11588532
The adenosine subtype 1 (A1) receptor, which may influence cardiac function and modulate renal function, may have particular relevance in congestive heart failure (CHF). However, the effects of A1 receptor...
8.
Etoh T, Joffs C, Deschamps A, Davis J, DOWDY K, Hendrick J, et al.
Am J Physiol Heart Circ Physiol . 2001 Aug; 281(3):H987-94. PMID: 11514263
A structural event during the evolution of a myocardial infarction (MI) is left ventricular (LV) remodeling. The mechanisms that contribute to early changes in LV myocardial remodeling in the post-MI...
9.
Sivasubramanian N, Coker M, Kurrelmeyer K, Maclellan W, Demayo F, Spinale F, et al.
Circulation . 2001 Aug; 104(7):826-31. PMID: 11502710
Background: The mechanisms responsible for tumor necrosis factor (TNF)-induced LV structural remodeling in the adult heart are not known. Methods And Results: We generated a line of transgenic mice (MHCsTNF)...
10.
Joffs C, Walker C, HENDRICK J, Fary D, Almany D, Davis J, et al.
J Thorac Cardiovasc Surg . 2001 Aug; 122(2):365-70. PMID: 11479511
Background: The bioactive peptide endothelin-1 is elevated during and after cardiopulmonary bypass and exerts cardiovascular effects through its 2 receptor subtypes, endothelin-1A and endothelin-1B. Increased endothelin-1A receptor stimulation after cardiopulmonary...