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F Ferraguti

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Recent Articles
11.
Cope D, Wulff P, Oberto A, Aller M, Capogna M, Ferraguti F, et al.
Neuropharmacology . 2004 May; 47(1):17-34. PMID: 15165831
Agonists of the allosteric benzodiazepine site of GABAA receptors bind at the interface of the alpha and gamma subunits. Here, we tested the in vivo contribution of the gamma2 subunit...
12.
Corti C, Aldegheri L, Somogyi P, Ferraguti F
Neuroscience . 2002 Mar; 110(3):403-20. PMID: 11906782
Group III metabotropic glutamate receptors (mGluRs) are selectively activated by L-2-amino-4-phosphonobutyrate (L-AP4), which produces depression of synaptic transmission. The relative contribution of different group III mGluRs to the effects of...
13.
Corti C, Xuereb J, Corsi M, Ferraguti F
Biochem Biophys Res Commun . 2001 Aug; 286(2):381-7. PMID: 11500049
We have recently described the genomic organisation of the human metabotropic glutamate receptor 3 (GRM3) gene. The putative promoter region is characterised by the presence of a CCAAT and Sp1...
14.
Mion S, Corti C, Neki A, Shigemoto R, Corsi M, Fumagalli G, et al.
Mol Cell Neurosci . 2001 Jun; 17(6):957-72. PMID: 11414786
Alternative splicing in the mGluR5 gene generates two different receptor isoforms, of which expression is developmentally regulated. However, little is known about the functional significance of mGluR5 splice variants. We...
15.
Corti C, Sala C, Yang F, Corsi M, Xuereb J, Ferraguti F
J Neurogenet . 2001 May; 14(4):207-25, 271. PMID: 11342382
In this study, the genomic organization of the human metabotropic glutamate receptor subtype 3 (mGluR3) gene has been determined. We have identified two transcription initiation sites and the polyadenylation signal...
16.
Ferraguti F, Corti C, Valerio E, Mion S, Xuereb J
Exp Brain Res . 2001 Apr; 137(1):1-11. PMID: 11310162
All forms of brain injury induce activation of astrocytes, although different types of injury induce different astrocytic responses. Activated astrocytes are characterised by hypertrophy, proliferation and increased expression of glial...
17.
Mateos J, Benitez R, Elezgarai I, Azkue J, Lazaro E, Osorio A, et al.
J Neurochem . 2000 Feb; 74(3):1301-9. PMID: 10693964
Several metabotropic glutamate receptor (mGluR) subtypes have been identified in the cerebellar cortex that are targeted to different compartments in cerebellar cells. In this study, preembedding immunocytochemical methods for electron...
18.
Ferraguti F, Corsi M, Nakanishi S, Corti C
Eur J Neurosci . 1999 May; 11(6):2073-2082. PMID: 10336676
Activation of metabotropic glutamate receptors (mGluRs) leads to modulation of a variety of second messenger pathways probably including the mitogen-activated protein kinase (MAPK) extracellular signal-regulated protein kinases (ERK). MAPK play...
19.
Corti C, Restituito S, Rimland J, Brabet I, Corsi M, Pin J, et al.
Eur J Neurosci . 1999 Jan; 10(12):3629-41. PMID: 9875342
Novel mRNA isoforms for two members of the group III metabotropic glutamate receptors (mGluRs), called mGluR7b and mGluR8b, were identified from rat brain cerebral cortex and hippocampus. In both cases,...
20.
Ferraguti F, Conquet F, Corti C, Grandes P, Kuhn R, Knopfel T
J Comp Neurol . 1998 Oct; 400(3):391-407. PMID: 9779943
Alternative splicing has been shown to occur at the metabotropic glutamate receptor 1 (mGluR1) gene. Three main isoforms that differ in their carboxy-termini have been described so far and named...