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F E Simons

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Articles 173
Citations 1670
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Recent Articles
1.
Simons F
Postgrad Med . 2009 Aug; 106(7 Suppl):7-11. PMID: 19667495
Histamine, a pivotal mediator of inflammation, has been the target of therapeutic intervention in allergic disorders for the better part of the past century. During this time, the benefit-to-risk profiles...
2.
Simons F, Chan E, Gu X, Simons K
J Allergy Clin Immunol . 2001 Dec; 108(6):1040-4. PMID: 11742286
Background: Little information is available about administration of an accurate epinephrine dose to infants experiencing anaphylaxis outside the hospital setting. Objective: Our purpose was to perform a prospective, controlled study...
3.
Kozyrskyj A, Mustard C, Simons F
Arch Pediatr Adolesc Med . 2001 Nov; 155(11):1219-24. PMID: 11695930
Background: Low-income children with asthma are less likely to receive inhaled corticosteroid prescriptions that can prevent asthma morbidity. Objective: To determine whether the receipt of inhaled corticosteroids in children with...
4.
Peng Z, Xu W, James A, Lam H, Sun D, Cheng L, et al.
Int Immunol . 2001 Nov; 13(12):1445-52. PMID: 11717185
Accurate diagnosis of mosquito allergy has been precluded by the difficulty of obtaining salivary allergens. In this study, we expressed, purified, characterized and investigated the clinical relevance of a recombinant...
5.
Simons F, Gu X, Simons K
J Allergy Clin Immunol . 2001 Nov; 108(5):871-3. PMID: 11692118
We report a prospective, randomized, blinded, placebo-controlled, 6-way crossover study of intramuscular versus subcutaneous injection of epinephrine in young men. Peak plasma epinephrine concentrations were significantly higher (P < .01)...
6.
Kozyrskyj A, Mustard C, Cheang M, Simons F
CMAJ . 2001 Oct; 165(7):897-902. PMID: 11599328
Background: Drug benefit policies are an important determinant of a population's use of prescription drugs. This study was undertaken to determine whether a change in a provincial drug benefit policy,...
7.
Simons F, Peterson S, Black C
Ann Allergy Asthma Immunol . 2001 Jun; 86(6):622-6. PMID: 11428733
Background: Epinephrine is life-saving in the treatment of anaphylaxis. A limited number of fixed-dose epinephrine formulations are available for out-of-hospital treatment of this disorder. Objective: To examine dispensing patterns for...
8.
Campbell J, Stinson M, Simons F, Rector E, HayGlass K
Hum Immunol . 2001 Jun; 62(7):668-78. PMID: 11423172
Cross-sectional analyses of human PBMC, plasma, and tissue have reported altered chemokine and/or chemokine receptor expression in several inflammatory diseases. Interpretation of such studies is difficult without data on the...
9.
Boulet L, Bai T, Becker A, Berube D, Beveridge R, Bowie D, et al.
Can Respir J . 2001 May; 8 Suppl A:5A-27A. PMID: 11360044
The objective of the present document is to review the impact of new information on the recommendations made in the last (1999) Canadian Asthma Consensus Guidelines. It includes relevant published...
10.
Simons F, Villa J, Lee B, Teper A, Lyttle B, Aristizabal G, et al.
J Pediatr . 2001 May; 138(5):694-8. PMID: 11343045
Objective: We tested the hypothesis that adding montelukast to budesonide would improve asthma control in children with inhaled glucocorticoid-dependent persistent asthma. Study Design: In a multicenter, randomized, double-blind, crossover study,...