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F E Hargreave

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Articles 264
Citations 4951
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Recent Articles
1.
Simms E, Kjarsgaard M, Denis S, Hargreave F, Nair P, Larche M
Clin Exp Allergy . 2013 Oct; 43(11):1226-35. PMID: 24152155
Background: Asthmatic patients are often differentiated based on their atopic status (atopic or nonatopic) and type of bronchitis (eosinophilic, neutrophilic, both, or neither). There is evidence supporting a central role...
2.
Nair P, Gaga M, Zervas E, Alagha K, Hargreave F, OByrne P, et al.
Clin Exp Allergy . 2012 Jun; 42(7):1097-103. PMID: 22702508
Background: Increased numbers of neutrophils are reported in the airways of patients with severe asthma. It is not clear if they contribute to the lack of control and severity. There...
3.
Kelly M, Efthimiadis A, Hargreave F
Methods Mol Med . 2011 Feb; 56:77-91. PMID: 21336891
Sputum consists of a mixture of mucus, inflammatory and epithelial cells, and cellular degradation products from the lower respiratory tract. In normal subjects, the inflammatory cells are mainly neutrophils and...
4.
Dolovich J, Greenbaum J, Bandouvakis J, Hargreave F
Can Fam Physician . 2011 Feb; 25:1221-4. PMID: 21297799
The family physician is ideally situated to deal with most chronic-recurrent nasal problems. The physician is alerted to the real problem by the recognition that terms such as 'sinus' and...
5.
Hargreave F, Cartier A, Ryan G, Kenworthy M, Dolovich J
Can Fam Physician . 2011 Feb; 25:1207-10. PMID: 21297796
The objectives of treating asthma are to control symptoms by a minimum of medication, and to prevent severe attacks in the future. However, before these can be achieved the presence...
6.
Hargreave F, Nair P
Clin Exp Allergy . 2009 Jul; 39(11):1652-8. PMID: 19622089
The diagnosis of asthma depends on what we mean by the word. Its definition continues to be controversial because there is no single genetic or environmental cause. Addressed from a...
7.
Chakir J, Loubaki L, Laviolette M, Milot J, Biardel S, Jayaram L, et al.
Eur Respir J . 2009 Jul; 35(1):48-53. PMID: 19608584
Normalisation of eosinophil counts in sputum of asthmatic patients reduces eosinophilic exacerbations. However, the effect of this strategy on airway remodelling remains to be determined. We compared bronchial inflammation and...
8.
Todd D, Armstrong S, DSilva L, Allen C, Hargreave F, Parameswaran K
Clin Exp Allergy . 2007 Jun; 37(7):1049-54. PMID: 17581198
Background: Several observational studies have demonstrated an association between obesity and asthma. Studies evaluating exhaled nitric oxide levels and obesity have revealed that a higher body mass index (BMI) is...
9.
Jayaram L, Labiris N, Efthimiadis A, Valchos-Mayer H, Hargreave F, Freitag A
Can Respir J . 2007 Mar; 14(2):99-103. PMID: 17372637
Background: Technical factors relating to processing viscid sputum in cystic fibrosis (CF) and their influence on the reproducibility and validity of cell counts need to be evaluated. In addition, the...
10.
Hargreave F, Leigh R, Parameswaran K
Lancet . 2006 Oct; 368(9545):1415-6. PMID: 17055932
No abstract available.