F C van Gils
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Explore the profile of F C van Gils including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
27
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Recent Articles
1.
van Gils F, van Teeffelen M, Neelis K, Hendrikx J, Burger H, van Leen R, et al.
Blood
. 1995 Jul;
86(2):592-7.
PMID: 7541670
To understand the hematopoietic and nonhematopoietic responses to interleukin-3 (IL-3), expression of cell-surface IL-3 receptors (IL-3R) was examined on bone marrow (BM) cells and peripheral blood (PB) cells of rhesus...
2.
van Gils F, Westerman Y, Visser T, Burger H, van Leen R, Wagemaker G
Leukemia
. 1994 Apr;
8(4):648-51.
PMID: 8152259
During administration of homologous nonglycosylated IL-3 to rhesus monkeys, reversal of hematologic effects and disappearance of side effects suggested a neutralizing anti-IL-3 antibody response. Among a total of 20 monkeys...
3.
van Gils F, Budel L, Burger H, van Leen R, Lowenberg B, Wagemaker G
Exp Hematol
. 1994 Mar;
22(3):248-55.
PMID: 7509288
The relative affinity of recombinant human interleukin-3 (IL-3) binding to normal rhesus monkey bone marrow cells was found to be 25- to 50-fold less than that of homologous IL-3, which...
4.
van Gils F, Mulder A, van den Bos C, Burger H, van Leen R, Wagemaker G
Am J Pathol
. 1993 Dec;
143(6):1621-33.
PMID: 8256852
Interleukin-3 treatment of juvenile rhesus monkeys elicits a dose- and time-dependent syndrome that includes urticaria, palpable lymph nodes, splenomegaly, thrombocytopenia, anemia, vomiting, diarrhea, intestinal bleeding, edema, and arthritis, apart from...
5.
van Gils F, Westerman Y, van den Bos C, Burger H, van Leen R, Wagemaker G
Leukemia
. 1993 Oct;
7(10):1602-7.
PMID: 8412321
To design an interleukin-3 (IL-3) administration schedule for optimal hemopoietic effectiveness, serum half-life (t1/2) was determined after intravenous (i.v) and subcutaneous (s.c.) bolus injections. The initial t1/2 in serum after...
6.
Wognum A, van Gils F, Wagemaker G
Blood
. 1993 Apr;
81(8):2036-43.
PMID: 8097119
The expression of receptors for interleukin-6 (IL-6) on human and rhesus monkey peripheral blood and bone marrow (BM) cells was examined by multiparameter flow cytometry after staining with biologically active,...
7.
van den Bos C, van Gils F, Bartstra R, Wagemaker G
Cytometry
. 1992 Jan;
13(6):659-62.
PMID: 1451598
A rapid and reliable method for longitudinal studies on the degree of red cell chimerism following bone marrow transplantation of alpha-thalassemic recipient mice is presented. Blood obtained by tail clipping...
8.
Wagemaker G, van Gils F, Burger H, Dorssers L, van Leen R, Persoon N, et al.
Blood
. 1990 Dec;
76(11):2235-41.
PMID: 2257298
Recombinant rhesus monkey interleukin-3 (IL-3) was administered to normal rhesus monkeys in graded doses ranging from 3 to 30 micrograms/kg/d subcutaneously for 30 consecutive days or given as a continuous...
9.
Wagemaker G, Burger H, van Gils F, van Leen R, Wielenga J
Biotherapy
. 1990 Jan;
2(4):337-45.
PMID: 2268499
Interleukin-3 (IL-3) is a hemopoietic growth factor involved in the survival, proliferation and differentiation of multipotent hemopoietic cells. In five mammalian species, including man, the gene encoding IL-3 has been...